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Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception

Breast cancer (BC) diagnosis and treatment have become a cumulative long-standing chronic disease impairment, causing stress and turning into an allostatic load (AL) framework. This study aimed to investigate the relationship between physical issues and mental health in patients with BC after medica...

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Autores principales: Irelli, Azzurra, Ranieri, Jessica, Sirufo, Maria Maddalena, De Pietro, Francesca, Casalena, Pamela, Ginaldi, Lia, Cannita, Katia, Di Giacomo, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031666/
https://www.ncbi.nlm.nih.gov/pubmed/35456237
http://dx.doi.org/10.3390/jcm11082144
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author Irelli, Azzurra
Ranieri, Jessica
Sirufo, Maria Maddalena
De Pietro, Francesca
Casalena, Pamela
Ginaldi, Lia
Cannita, Katia
Di Giacomo, Dina
author_facet Irelli, Azzurra
Ranieri, Jessica
Sirufo, Maria Maddalena
De Pietro, Francesca
Casalena, Pamela
Ginaldi, Lia
Cannita, Katia
Di Giacomo, Dina
author_sort Irelli, Azzurra
collection PubMed
description Breast cancer (BC) diagnosis and treatment have become a cumulative long-standing chronic disease impairment, causing stress and turning into an allostatic load (AL) framework. This study aimed to investigate the relationship between physical issues and mental health in patients with BC after medical treatment. We conducted an observational study of 61 female patients with BC, and clinical and psychological markers have been detected. We conducted descriptive statistics, ANOVA analyses, correlations, and mediation analyses to verify the effect of the comorbidity index on psychological dimensions. The findings showed high levels of distress and moderate pain, and 32.8% of the patients showed moderate physical impairment. Significant effects of “age” and “physical issues” were found. The adult group reported a higher incidence of physical issues, and the group of patients reporting moderate physical impairment seemed more depressed than patients with mild physical issues. Finally, the comorbidity condition mediated the presence of signs of depression. Patients with BC seemed to experience negative emotions related to comorbidities associated with compromised activities of daily living. Our findings highlighted allostatic overload as a predictive framework to better understand the mental health of women with BC diagnoses to tailor effective psychological treatments for enhanced recovery.
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spelling pubmed-90316662022-04-23 Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception Irelli, Azzurra Ranieri, Jessica Sirufo, Maria Maddalena De Pietro, Francesca Casalena, Pamela Ginaldi, Lia Cannita, Katia Di Giacomo, Dina J Clin Med Article Breast cancer (BC) diagnosis and treatment have become a cumulative long-standing chronic disease impairment, causing stress and turning into an allostatic load (AL) framework. This study aimed to investigate the relationship between physical issues and mental health in patients with BC after medical treatment. We conducted an observational study of 61 female patients with BC, and clinical and psychological markers have been detected. We conducted descriptive statistics, ANOVA analyses, correlations, and mediation analyses to verify the effect of the comorbidity index on psychological dimensions. The findings showed high levels of distress and moderate pain, and 32.8% of the patients showed moderate physical impairment. Significant effects of “age” and “physical issues” were found. The adult group reported a higher incidence of physical issues, and the group of patients reporting moderate physical impairment seemed more depressed than patients with mild physical issues. Finally, the comorbidity condition mediated the presence of signs of depression. Patients with BC seemed to experience negative emotions related to comorbidities associated with compromised activities of daily living. Our findings highlighted allostatic overload as a predictive framework to better understand the mental health of women with BC diagnoses to tailor effective psychological treatments for enhanced recovery. MDPI 2022-04-12 /pmc/articles/PMC9031666/ /pubmed/35456237 http://dx.doi.org/10.3390/jcm11082144 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Irelli, Azzurra
Ranieri, Jessica
Sirufo, Maria Maddalena
De Pietro, Francesca
Casalena, Pamela
Ginaldi, Lia
Cannita, Katia
Di Giacomo, Dina
Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception
title Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception
title_full Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception
title_fullStr Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception
title_full_unstemmed Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception
title_short Allostatic Load as an Insight into the Psychological Burden after Primary Treatment in Women with Breast Cancer: Influence of Physical Side Effects and Pain Perception
title_sort allostatic load as an insight into the psychological burden after primary treatment in women with breast cancer: influence of physical side effects and pain perception
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031666/
https://www.ncbi.nlm.nih.gov/pubmed/35456237
http://dx.doi.org/10.3390/jcm11082144
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