Discovery of MurA Inhibitors as Novel Antimicrobials through an Integrated Computational and Experimental Approach

The bacterial cell wall is essential for protecting bacteria from the surrounding environment and maintaining the integrity of bacteria cells. The MurA enzyme, which is an essential enzyme involved in bacterial cell wall synthesis, could be a good drug target for antibiotics. Although fosfomycin is...

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Detalles Bibliográficos
Autores principales: Zhang, Fangyuan, Graham, Joshua, Zhai, Tianhua, Liu, Yanhong, Huang, Zuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031695/
https://www.ncbi.nlm.nih.gov/pubmed/35453279
http://dx.doi.org/10.3390/antibiotics11040528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031695/
https://www.ncbi.nlm.nih.gov/pubmed/35453279
http://dx.doi.org/10.3390/antibiotics11040528

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