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Discovery of MurA Inhibitors as Novel Antimicrobials through an Integrated Computational and Experimental Approach
The bacterial cell wall is essential for protecting bacteria from the surrounding environment and maintaining the integrity of bacteria cells. The MurA enzyme, which is an essential enzyme involved in bacterial cell wall synthesis, could be a good drug target for antibiotics. Although fosfomycin is...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031695/ https://www.ncbi.nlm.nih.gov/pubmed/35453279 http://dx.doi.org/10.3390/antibiotics11040528 |