Cargando…

Distribution of Charged Residues Affects the Average Size and Shape of Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDPs) are ensembles of interconverting conformers whose conformational properties are governed by several physico-chemical factors, including their amino acid composition and the arrangement of oppositely charged residues within the primary structure. In this work,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bianchi, Greta, Mangiagalli, Marco, Barbiroli, Alberto, Longhi, Sonia, Grandori, Rita, Santambrogio, Carlo, Brocca, Stefania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031945/ https://www.ncbi.nlm.nih.gov/pubmed/35454150 http://dx.doi.org/10.3390/biom12040561

Ejemplares similares

Relevance of Electrostatic Charges in Compactness, Aggregation, and Phase Separation of Intrinsically Disordered Proteins
por: Bianchi, Greta, et al.
Publicado: (2020)

Extracting structural information from charge-state distributions of intrinsically disordered proteins by non-denaturing electrospray-ionization mass spectrometry
por: Testa, Lorenzo, et al.
Publicado: (2013)

Liquid–Liquid Phase Separation by Intrinsically Disordered Protein Regions of Viruses: Roles in Viral Life Cycle and Control of Virus–Host Interactions
por: Brocca, Stefania, et al.
Publicado: (2020)

Liaisons dangereuses: Intrinsic Disorder in Cellular Proteins Recruited to Viral Infection-Related Biocondensates
por: Bianchi, Greta, et al.
Publicado: (2023)

pH-Dependent Aggregation in Intrinsically Disordered Proteins Is Determined by Charge and Lipophilicity
por: Santos, Jaime, et al.
Publicado: (2020)

Intramolecular interactions stabilizing compact conformations of the intrinsically disordered kinase-inhibitor domain of Sic1: a molecular dynamics investigation
por: Lambrughi, Matteo, et al.
Publicado: (2012)

Per Aspera ad Chaos: Vladimir Uversky’s Odyssey through the Strange World of Intrinsically Disordered Proteins
por: Kulkarni, Prakash, et al.
Publicado: (2023)

Depicting Conformational Ensembles of α-Synuclein by Single Molecule Force Spectroscopy and Native Mass Spectroscopy
por: Corti, Roberta, et al.
Publicado: (2019)

Embelin binds to human neuroserpin and impairs its polymerisation
por: Saga, Giorgia, et al.
Publicado: (2016)

Contact Lens Wear Induces Alterations of Lactoferrin Functionality in Human Tears
por: Ponzini, Erika, et al.
Publicado: (2022)

A new technique for predicting intrinsically disordered regions based on average distance map constructed with inter-residue average distance statistics
por: Shimomura, Takumi, et al.
Publicado: (2019)

Mass spectrometry‐based tear proteomics for noninvasive biomarker discovery
por: Ponzini, Erika, et al.
Publicado: (2021)

Charge Division and Intrinsic Pulse Shaping in Drift Tubes
por: Deile, M, et al.
Publicado: (1996)

Charging for computer usage with average cost pricing
por: Landau, K
Publicado: (1973)

An estimate of the average charged multiplicity at ISR energies
por: Breidenbach, M, et al.
Publicado: (1972)

Chiral hemicucurbit[8]uril as an anion receptor: selectivity to size, shape and charge distribution
por: Kaabel, Sandra, et al.
Publicado: (2017)

Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins
por: Beveridge, Rebecca, et al.
Publicado: (2019)

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β(2)-Microglobulin
por: Halabelian, Levon, et al.
Publicado: (2014)

Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry
por: Luise, Arianna, et al.
Publicado: (2021)

Evolution of the average avalanche shape with the universality class
por: Laurson, Lasse, et al.
Publicado: (2013)

In Silico Generation of Peptides by Replica Exchange Monte Carlo: Docking-Based Optimization of Maltose-Binding-Protein Ligands
por: Russo, Anna, et al.
Publicado: (2015)

Correction: In Silico Generation of Peptides by Replica Exchange Monte Carlo: Docking-Based Optimization of Maltose-Binding-Protein Ligands
por: Russo, Anna, et al.
Publicado: (2016)

W$^{2}$ and Q$^{2}$ dependence of average multiplicities and x$_{F}$ distributions of charged pions
por: Dengler, F
Publicado: (1986)

The intrinsic dependence structure of peak, volume, duration, and average intensity of hyetographs and hydrographs
por: Serinaldi, Francesco, et al.
Publicado: (2013)

Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity
por: Carija, Anita, et al.
Publicado: (2019)

Single-Tear Proteomics: A Feasible Approach to Precision Medicine
por: Ponzini, Erika, et al.
Publicado: (2021)

α-Synuclein is a Novel Microtubule Dynamase
por: Cartelli, Daniele, et al.
Publicado: (2016)

The average charged-particle multiplicity as a function of the centre-of-mass energy.
por: ATLAS Collaboration
Publicado: (2015)

Investigation of the Average Shape and Principal Variations of the Human Talus Bone Using Statistic Shape Model
por: Liu, Tao, et al.
Publicado: (2020)

Modulation of Asymmetric Flux in Heterotypic Gap Junctions by Pore Shape, Particle Size and Charge
por: Mondal, Abhijit, et al.
Publicado: (2017)

Perception of the average size of multiple objects in chimpanzees (Pan troglodytes)
por: Imura, Tomoko, et al.
Publicado: (2017)

Fast and accurate average genome size and 16S rRNA gene average copy number computation in metagenomic data
por: Pereira-Flores, Emiliano, et al.
Publicado: (2019)

Average charged multiplicity of events containing heavy quarks in e+e- annihilation
por: Schumm, B A, et al.
Publicado: (1992)

Bifid Shape Is Intrinsic to Bifidobacterium adolescentis
por: Dhanashree,, et al.
Publicado: (2017)

Size, shape, charge and “stealthy” surface: Carrier properties affect the drug circulation time in vivo
por: Di, Jinwei, et al.
Publicado: (2021)

Size-dependent shape distributions of platinum nanoparticles
por: Ding, Ruikang, et al.
Publicado: (2022)

Requirements to Determine the Average Pore Size of Nanoporous Media Using Ultrasound
por: Schappert, Klaus, et al.
Publicado: (2018)

Size and Velocity Distribution of Negatively Charged Helium Nanodroplets
por: Laimer, F., et al.
Publicado: (2021)

Measurement of event shape distributions, their averages and Jet rates at sqrt(s) =161 GeV and 172 GeV
por: Grefrath, A
Publicado: (1997)

Disulfide driven folding for a conditionally disordered protein
por: Fraga, Hugo, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_smmo2mb6tts6trb85gom59r9nh