Cargando…

Preliminary Research of Main Components of Dll4/ Notch-VEGF Signaling Pathway Under High-Glucose Stimulation in vitro

PURPOSE: To establish a high-glucose (HG) stressed cell model and study the expression of main components of the Dll4/Notch-VEGF signaling pathway under high-glucose stimulation. METHODS: A model of HG-conditioned cells (human umbilical vein endothelial cells, HUVECs) was first established, and then...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Na, Xiao, Linghui, Tao, Zheng, Zheng, Yanlin, Wang, Wanjie, Huang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031991/ https://www.ncbi.nlm.nih.gov/pubmed/35464260 http://dx.doi.org/10.2147/DMSO.S355004

Ejemplares similares

The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro
por: Tveriakhina, Lena, et al.
Publicado: (2018)

Association of Dll4/Notch and HIF-1a -VEGF Signaling in the Angiogenesis of Missed Abortion
por: Fang, Yan, et al.
Publicado: (2013)

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
por: Geffers, Insa, et al.
Publicado: (2007)

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo
por: Preuße, Kristina, et al.
Publicado: (2015)

Spatial patterning of the Notch ligand Dll4 controls endothelial sprouting in vitro
por: Tiemeijer, L. A., et al.
Publicado: (2018)

Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine
por: Shimizu, Hiromichi, et al.
Publicado: (2014)

Tryptanthrin inhibits tumor angiogenesis via Notch/Dll4 signaling pathway in zebrafish
por: Lin, Meimei, et al.
Publicado: (2023)

Therapeutic promise and challenges of targeting DLL4/NOTCH1
por: Yan, Minhong
Publicado: (2011)

Maintenance of Bone Homeostasis by DLL1‐Mediated Notch Signaling
por: Muguruma, Yukari, et al.
Publicado: (2017)

Foxc Transcription Factors Directly Regulate Dll4 and Hey2 Expression by Interacting with the VEGF-Notch Signaling Pathways in Endothelial Cells
por: Hayashi, Hisaki, et al.
Publicado: (2008)

Polychlorinated biphenyls target Notch/Dll and VEGF R2 in the mouse placenta and human trophoblast cell lines for their anti-angiogenic effects
por: Kalkunte, Satyan, et al.
Publicado: (2017)

Xuan Bi Tong Yu Fang Promotes Angiogenesis via VEGF-Notch1/Dll4 Pathway in Myocardial Ischemic Rats
por: Li, Shuangdi, et al.
Publicado: (2020)

Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium
por: Hirano, Ken-ichi, et al.
Publicado: (2022)

Dll4-Notch signaling as a therapeutic target in tumor angiogenesis
por: Kuhnert, Frank, et al.
Publicado: (2011)

MPDZ promotes DLL4-induced Notch signaling during angiogenesis
por: Tetzlaff, Fabian, et al.
Publicado: (2018)

DLL3 regulates Notch signaling in small cell lung cancer
por: Kim, Jun W., et al.
Publicado: (2022)

Inhibition of Dll4/Notch1 pathway promotes angiogenesis of Masquelet’s induced membrane in rats
por: Tang, Qian, et al.
Publicado: (2018)

Targeting the DLL/Notch Signaling Pathway in Cancer: Challenges and Advances in Clinical Development
por: You, Weon-Kyoo, et al.
Publicado: (2023)

Expressions and Prognostic Values of Notch3 and DLL4 in Human Breast Cancer
por: Wang, Lin, et al.
Publicado: (2023)

Gm364 coordinates MIB2/DLL3/Notch2 to regulate female fertility through AKT activation
por: Chen, Liang-Jian, et al.
Publicado: (2021)

Influence of Dll4 via HIF-1α-VEGF Signaling on the Angiogenesis of Choroidal Neovascularization under Hypoxic Conditions
por: Dong, Xiao, et al.
Publicado: (2011)

Dll4-Notch Signalling Blockade Synergizes Combined Ultrasound-Stimulated Microbubble and Radiation Therapy in Human Colon Cancer Xenografts
por: El Kaffas, Ahmed, et al.
Publicado: (2014)

Suppression of human colon tumor by EERAC through regulating Notch/DLL4/Hes pathway inhibiting angiogenesis in vivo
por: Yuan, Chenchen, et al.
Publicado: (2021)

Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM
por: Bone, Robert A., et al.
Publicado: (2014)

The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells
por: Sales-Dias, Joana, et al.
Publicado: (2019)

Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer
por: Kumar, Sushil, et al.
Publicado: (2018)

Activity of the mouse Notch ligand DLL1 is sensitive to C-terminal tagging in vivo
por: Schuster-Gossler, Karin, et al.
Publicado: (2021)

Feedback regulation of Notch signaling and myogenesis connected by MyoD–Dll1 axis
por: Zhang, Haifeng, et al.
Publicado: (2021)

The potential value of Notch1 and DLL1 in the diagnosis and prognosis of patients with active TB
por: Xie, Jinling, et al.
Publicado: (2023)

NOTCH2/NOTCH3/DLL3/MAML1/ADAM17 signaling network is associated with ovarian cancer
por: Jia, Dongyu, et al.
Publicado: (2019)

The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions
por: Lobov, Ivan, et al.
Publicado: (2018)

Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway
por: Oliveira, Rebeca Hannah M, et al.
Publicado: (2023)

Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells
por: López-Guerra, Mónica, et al.
Publicado: (2019)

Dll4–Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice
por: Billiard, Fabienne, et al.
Publicado: (2012)

O-fucosylation of the Notch Ligand mDLL1 by POFUT1 Is Dispensable for Ligand Function
por: Müller, Julia, et al.
Publicado: (2014)

Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion
por: Ubezio, Benedetta, et al.
Publicado: (2016)

RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain
por: Bridges, Esther, et al.
Publicado: (2020)

Upregulated expression of Notch1/4 - JAG-1/DLL-1 detected in allergic rhinitis
por: Hjalmarsson, Eric, et al.
Publicado: (2023)

Characterization of Two Distinct Lymphoproliferative Diseases Caused by Ectopic Expression of the Notch Ligand DLL4 on T Cells
por: Xiong, Huizhong, et al.
Publicado: (2013)

The Notch ligand Delta-like 4 (DLL4) as a target in angiogenesis-based cancer therapy?
por: Brzozowa, Marlena, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b0cpgbopi8m4qccf93auhqcj09