Cargando…

Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm

Russell’s viper (Daboia russelii), one of the ‘Big Four’ venomous snakes in India, is responsible for the majority of snakebite-induced deaths and permanent disabilities. Russell’s viper bites are known to induce bleeding/clotting abnormalities, as well as myotoxic, nephrotoxic, cytotoxic and neurot...

Descripción completa

Detalles Bibliográficos
Autores principales: Senthilkumaran, Subramanian, Miller, Stephen W., Williams, Harry F., Vaiyapuri, Rajendran, Savania, Ravi, Elangovan, Namasivayam, Thirumalaikolundusubramanian, Ponniah, Patel, Ketan, Vaiyapuri, Sakthivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032084/
https://www.ncbi.nlm.nih.gov/pubmed/35448869
http://dx.doi.org/10.3390/toxins14040260
_version_ 1784692553176580096
author Senthilkumaran, Subramanian
Miller, Stephen W.
Williams, Harry F.
Vaiyapuri, Rajendran
Savania, Ravi
Elangovan, Namasivayam
Thirumalaikolundusubramanian, Ponniah
Patel, Ketan
Vaiyapuri, Sakthivel
author_facet Senthilkumaran, Subramanian
Miller, Stephen W.
Williams, Harry F.
Vaiyapuri, Rajendran
Savania, Ravi
Elangovan, Namasivayam
Thirumalaikolundusubramanian, Ponniah
Patel, Ketan
Vaiyapuri, Sakthivel
author_sort Senthilkumaran, Subramanian
collection PubMed
description Russell’s viper (Daboia russelii), one of the ‘Big Four’ venomous snakes in India, is responsible for the majority of snakebite-induced deaths and permanent disabilities. Russell’s viper bites are known to induce bleeding/clotting abnormalities, as well as myotoxic, nephrotoxic, cytotoxic and neurotoxic envenomation effects. In addition, they have been reported to induce rare envenomation effects such as priapism, sialolithiasis and splenic rupture. However, Russell’s viper bite-induced pseudoaneurysm (PA) has not been previously reported. PA or false aneurysm is a rare phenomenon that occurs in arteries following traumatic injuries including some animal bites, and it can become a life-threatening condition if not treated promptly. Here, we document two clinical cases of Russell’s viper bites where PA has developed, despite antivenom treatment. Notably, a non-surgical procedure, ultrasound-guided compression (USGC), either alone, or in combination with thrombin was effectively used in both the cases to treat the PA. Following this procedure and additional measures, the patients made complete recoveries without the recurrence of PA which were confirmed by subsequent examination and ultrasound scans. These data demonstrate the development of PA as a rare complication following Russell’s viper bites and the effective use of a simple, non-surgical procedure, USGC for the successful treatment of PA. These results will create awareness among healthcare professionals on the development of PA and the use of USGC in snakebite victims following bites from Russell’s vipers, as well as other viper bites.
format Online
Article
Text
id pubmed-9032084
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-90320842022-04-23 Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm Senthilkumaran, Subramanian Miller, Stephen W. Williams, Harry F. Vaiyapuri, Rajendran Savania, Ravi Elangovan, Namasivayam Thirumalaikolundusubramanian, Ponniah Patel, Ketan Vaiyapuri, Sakthivel Toxins (Basel) Article Russell’s viper (Daboia russelii), one of the ‘Big Four’ venomous snakes in India, is responsible for the majority of snakebite-induced deaths and permanent disabilities. Russell’s viper bites are known to induce bleeding/clotting abnormalities, as well as myotoxic, nephrotoxic, cytotoxic and neurotoxic envenomation effects. In addition, they have been reported to induce rare envenomation effects such as priapism, sialolithiasis and splenic rupture. However, Russell’s viper bite-induced pseudoaneurysm (PA) has not been previously reported. PA or false aneurysm is a rare phenomenon that occurs in arteries following traumatic injuries including some animal bites, and it can become a life-threatening condition if not treated promptly. Here, we document two clinical cases of Russell’s viper bites where PA has developed, despite antivenom treatment. Notably, a non-surgical procedure, ultrasound-guided compression (USGC), either alone, or in combination with thrombin was effectively used in both the cases to treat the PA. Following this procedure and additional measures, the patients made complete recoveries without the recurrence of PA which were confirmed by subsequent examination and ultrasound scans. These data demonstrate the development of PA as a rare complication following Russell’s viper bites and the effective use of a simple, non-surgical procedure, USGC for the successful treatment of PA. These results will create awareness among healthcare professionals on the development of PA and the use of USGC in snakebite victims following bites from Russell’s vipers, as well as other viper bites. MDPI 2022-04-06 /pmc/articles/PMC9032084/ /pubmed/35448869 http://dx.doi.org/10.3390/toxins14040260 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Senthilkumaran, Subramanian
Miller, Stephen W.
Williams, Harry F.
Vaiyapuri, Rajendran
Savania, Ravi
Elangovan, Namasivayam
Thirumalaikolundusubramanian, Ponniah
Patel, Ketan
Vaiyapuri, Sakthivel
Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm
title Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm
title_full Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm
title_fullStr Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm
title_full_unstemmed Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm
title_short Ultrasound-Guided Compression Method Effectively Counteracts Russell’s Viper Bite-Induced Pseudoaneurysm
title_sort ultrasound-guided compression method effectively counteracts russell’s viper bite-induced pseudoaneurysm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032084/
https://www.ncbi.nlm.nih.gov/pubmed/35448869
http://dx.doi.org/10.3390/toxins14040260
work_keys_str_mv AT senthilkumaransubramanian ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT millerstephenw ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT williamsharryf ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT vaiyapurirajendran ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT savaniaravi ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT elangovannamasivayam ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT thirumalaikolundusubramanianponniah ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT patelketan ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm
AT vaiyapurisakthivel ultrasoundguidedcompressionmethodeffectivelycounteractsrussellsviperbiteinducedpseudoaneurysm