Novel Protein–Protein Interactions Highlighting the Crosstalk between Hypoplastic Left Heart Syndrome, Ciliopathies and Neurodevelopmental Delays

Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease (CHD) affecting 1 in 5000 newborns. We constructed the interactome of 74 HLHS-associated genes identified from a large-scale mouse mutagenesis screen, augmenting it with 408 novel protein–protein interactions (PPIs) using ou...

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Detalles Bibliográficos
Autores principales: Karunakaran, Kalyani B., Gabriel, George C., Balakrishnan, Narayanaswamy, Lo, Cecilia W., Ganapathiraju, Madhavi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032108/
https://www.ncbi.nlm.nih.gov/pubmed/35456433
http://dx.doi.org/10.3390/genes13040627

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