Relationship between Biodistribution and Tracer Kinetics of (11)C-Erlotinib, (18)F-Afatinib and (11)C-Osimertinib and Image Quality Evaluation Using Pharmacokinetic/Pharmacodynamic Analysis in Advanced Stage Non-Small Cell Lung Cancer Patients

Background: Patients with non-small cell lung cancer (NSCLC) driven by activating epidermal growth factor receptor (EGFR) mutations are best treated with therapies targeting EGFR, i.e., tyrosine kinase inhibitors (TKI). Radiolabeled EGFR-TKI and PET have been investigated to study EGFR-TKI kinetics...

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Detalles Bibliográficos
Autores principales: van de Stadt, Eveline Annette, Yaqub, Maqsood, Schuit, Robert C., Bartelink, Imke H., Leeuwerik, Anke F., Schwarte, Lothar A., de Langen, Adrianus J., Hendrikse, Harry, Bahce, Idris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032381/
https://www.ncbi.nlm.nih.gov/pubmed/35453931
http://dx.doi.org/10.3390/diagnostics12040883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032381/
https://www.ncbi.nlm.nih.gov/pubmed/35453931
http://dx.doi.org/10.3390/diagnostics12040883

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