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Targeting pancreatic cancer with combinatorial treatment of CPI-613 and inhibitors of lactate metabolism
Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of 10%. A stagnant high mortality rate over the last decades highlights the need for innovative therapeutic approaches. Pancreatic tumors pursue an altered metabolism in order to maintain energy generation und...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032382/ https://www.ncbi.nlm.nih.gov/pubmed/35452495 http://dx.doi.org/10.1371/journal.pone.0266601 |