Targeting pancreatic cancer with combinatorial treatment of CPI-613 and inhibitors of lactate metabolism

Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of 10%. A stagnant high mortality rate over the last decades highlights the need for innovative therapeutic approaches. Pancreatic tumors pursue an altered metabolism in order to maintain energy generation und...

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Detalles Bibliográficos
Autores principales: Kumstel, Simone, Schreiber, Tim, Goldstein, Lea, Stenzel, Jan, Lindner, Tobias, Joksch, Markus, Zhang, Xianbin, Wendt, Edgar Heinz Uwe, Schönrogge, Maria, Krause, Bernd, Vollmar, Brigitte, Zechner, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032382/
https://www.ncbi.nlm.nih.gov/pubmed/35452495
http://dx.doi.org/10.1371/journal.pone.0266601

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