Regulation of Mus81-Eme1 structure-specific endonuclease by Eme1 SUMO-binding and Rad3(ATR) kinase is essential in the absence of Rqh1(BLM) helicase

The Mus81-Eme1 structure-specific endonuclease is crucial for the processing of DNA recombination and late replication intermediates. In fission yeast, stimulation of Mus81-Eme1 in response to DNA damage at the G2/M transition relies on Cdc2(CDK1) and DNA damage checkpoint-dependent phosphorylation...

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Detalles Bibliográficos
Autores principales: Giaccherini, Cédric, Scaglione, Sarah, Coulon, Stéphane, Dehé, Pierre-Marie, Gaillard, Pierre-Henri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032445/
https://www.ncbi.nlm.nih.gov/pubmed/35452455
http://dx.doi.org/10.1371/journal.pgen.1010165

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