Cargando…

Discovery of 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenoxy)-chromen-4-one with Lipid Lowering Effects in Hepatocytes

The population with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) is increasing. However, no medicine is indicated for treating these diseases clinically nowadays. Therefore, there is an urgent need to develop a new drug to overcome NAFLD and NASH. Capillarisin, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Yi-Han, Yen, Chia-Hung, Lai, Chih-Chung, Lai, Hsuan-Yu, Hung, Hsin-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032471/ https://www.ncbi.nlm.nih.gov/pubmed/35455445 http://dx.doi.org/10.3390/ph15040449

Ejemplares similares

5,7-Dimethoxy-2-phenyl-4H-chromen-4-one
por: Nallasivam, Angannan, et al.
Publicado: (2009)

Modulation of Cyclins, p53 and Mitogen-Activated Protein Kinases Signaling in Breast Cancer Cell Lines by 4-(3,4,5-Trimethoxyphenoxy)benzoic Acid
por: Lee, Kuan-Han, et al.
Publicado: (2014)

8-Iodo-5,7-dimethoxy-4-methyl-2H-chromen-2-one
por: Pereira Silva, P. S., et al.
Publicado: (2011)

2-(5,7-Dimethoxy-4-oxo-4H-chromen-2-yl)phenyl 4-toluenesulfonate
por: Ramachandran, G., et al.
Publicado: (2008)

5,7-Dihydroxy-3,6-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one monohydrate
por: Mohammad, Akhtar, et al.
Publicado: (2010)

N′-(2,4-Dimethoxybenzylidene)-3,4,5-trihydroxybenzohydrazide ethanol solvate
por: Alhadi, Abeer A., et al.
Publicado: (2009)

5,7-dihydroxy-2-(3-hydroxy-4, 5-dimethoxy-phenyl)-chromen-4-one-a flavone from Bruguiera gymnorrhiza displaying anti-inflammatory properties
por: Barik, Rajib, et al.
Publicado: (2016)

2-Bromo-5,7-dimethoxy-4-phenylquinoline
por: Gopal, Veshal, et al.
Publicado: (2009)

6,8-Diiodo-5,7-dimethoxy-4-methylcoumarin
por: Pereira Silva, P. S., et al.
Publicado: (2010)

5,7-Bis(benzyloxy)-2-phenyl-4H-chromen-4-one
por: Nallasivam, Angannan, et al.
Publicado: (2008)

(E)-3,4,5-Trimethoxy-N′-[(4-oxo-4H-chromen-3-yl)methylidene]benzohydrazide
por: Ishikawa, Yoshinobu, et al.
Publicado: (2014)

Targeting allosteric site of AKT by 5,7-dimethoxy-1,4-phenanthrenequinone suppresses neutrophilic inflammation
por: Chen, Po-Jen, et al.
Publicado: (2019)

Hexaaqua(5,7-dihydroxy-4-oxo-2-phenyl-4H-chromene-8-sulfonato)calcium(II) 5,7-dihydroxy-4-oxo-2-phenyl-4H-chromene-8-sulfonate trihydrate
por: Liu, Bin, et al.
Publicado: (2008)

5,7-Dimethoxyisobenzofuran-1(3H)-one
por: Sun, Ming-Xue, et al.
Publicado: (2009)

Targeting Cancer Stem Cells with Novel 4-(4-Substituted phenyl)-5-(3,4,5-trimethoxy/3,4-dimethoxy)-benzoyl-3,4-dihydropyrimidine-2(1H)-one/thiones
por: Bhat, Mashooq Ahmad, et al.
Publicado: (2016)

5,7-Bis(benzyloxy)-2-[4-(benzyloxy)phenyl]-4H-chromen-4-one
por: Ren, Xu-Hong, et al.
Publicado: (2009)

(E)-3,4,5-Trimethoxy-N′-[(6-methoxy-4-oxo-4H-chromen-3-yl)methylidene]benzohydrazide monohydrate
por: Ishikawa, Yoshinobu, et al.
Publicado: (2014)

3,4,5-Trimethoxybenzohydrazidium chloride
por: Saeed, Aamer, et al.
Publicado: (2008)

3,4,5-Trihydroxybenzohydrazide
por: Ashiq, Uzma, et al.
Publicado: (2011)

3,4,5-Trimethoxyphenol
por: Jia, Xiao-Chuan, et al.
Publicado: (2012)

4′-Chloro-3′,5′-dimethoxyacetanilide
por: Li, Huiyu, et al.
Publicado: (2009)

2-Phenyl-4-(3,4,5-trimethoxybenzylidene)-1,3-oxazol-5(4H)-one
por: Sun, Yi-Feng, et al.
Publicado: (2008)

Anti-UVC Irradiation and Metal Chelation Properties of 6-Benzoyl-5,7-dihydroxy-4-phenyl-chromen-2-one: An Implications for Anti-Cataract Agent
por: Liao, Jiahn-Haur, et al.
Publicado: (2011)

3,4,5-Trihydroxybenzohydrazidium perchlorate–3,4,5-trihydroxybenzohydrazide–water (1/1/1)
por: A. Alhadi, Abeer, et al.
Publicado: (2011)

2-Phenyl-5,7-bis(prop-2-en-1-yloxy)-4H-chromen-4-one
por: Nallasivam, Angannan, et al.
Publicado: (2008)

5,7-Dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one methanol solvate monohydrate
por: Aree, Thammarat, et al.
Publicado: (2009)

(5,7-Dimethyl-2-oxo-2H-chromen-4-yl)methyl diethyldithiocarbamate
por: Kumar, K. Mahesh, et al.
Publicado: (2012)

Isopropyl 3,4,5-trihydroxybenzoate
por: Lan, Wei, et al.
Publicado: (2012)

3,4,5-Trihydroxybenzoic acid
por: Hirun, Namon, et al.
Publicado: (2011)

3,4-Dihydroxyphenyl 3,4,5-trimethoxybenzoate
por: Hong, Won Ki, et al.
Publicado: (2007)

3,4,5-Trimethoxy-4′-methylbiphenyl
por: Lahtinen, Manu, et al.
Publicado: (2013)

4-Hydroxy-3-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-2H-chromen-2-one
por: Mechi, Lassaad, et al.
Publicado: (2009)

Poly[(μ-5,7-dihydroxy-4-oxo-2-phenyl-4H-chromene-8-sulfonato)potassium(I)]
por: Liu, Bin, et al.
Publicado: (2008)

5,7-Dihydroxy-2-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-chromen-4-one
por: Adizov, Shahobiddin M., et al.
Publicado: (2013)

(5,7-Dimethyl-2-oxo-2H-chromen-4-yl)methyl pyrrolidine-1-carbodithioate
por: Mahabaleshwaraiah, N. M., et al.
Publicado: (2012)

N-Cyclohexyl-3,4,5-trimethoxybenzamide
por: Saeed, Aamer, et al.
Publicado: (2009)

Synthesis and Antiprotozoal Profile of 3,4,5‐Trisubstituted Isoxazoles
por: Rosa, Fernanda Andreia, et al.
Publicado: (2021)

(2E,5E)-2,5-Bis(3,4,5-trimethoxybenzylidene)cyclopentanone
por: Sun, Yi-Feng, et al.
Publicado: (2008)

4-Bromo-N-(3,4,5-trimethoxybenzylidene)aniline
por: Khalaji, Aliakbar Dehno, et al.
Publicado: (2009)

N-(4-Chlorophenyl)-3,4,5-trimethoxybenzamide
por: Saeed, Aamer, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_9kp05psv9d6eakmi2qgk17q8re