Recalibrating Interpretations of Aldosterone Assays Across the Physiologic Range: Immunoassay and Liquid Chromatography–Tandem Mass Spectrometry Measurements Under Multiple Controlled Conditions

CONTEXT: Clinicians frequently rely on aldosterone thresholds derived from older immunoassays to diagnose primary aldosteronism. Liquid chromatography–tandem mass spectrometry (LC-MS/MS) is increasingly widespread and reported to yield lower aldosterone concentrations. OBJECTIVE: Given the health im...

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Detalles Bibliográficos
Autores principales: Brown, Jenifer M, Auchus, Richard J, Honzel, Brooke, Luther, James M, Yozamp, Nicholas, Vaidya, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Clinical Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032635/
https://www.ncbi.nlm.nih.gov/pubmed/35475027
http://dx.doi.org/10.1210/jendso/bvac049

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