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Selective Anticancer Therapy Based on a HA-CD44 Interaction Inhibitor Loaded on Polymeric Nanoparticles
Hyaluronic acid (HA), through its interactions with the cluster of differentiation 44 (CD44), acts as a potent modulator of the tumor microenvironment, creating a wide range of extracellular stimuli for tumor growth, angiogenesis, invasion, and metastasis. An innovative antitumor treatment strategy...
Autores principales: | Espejo-Román, José M., Rubio-Ruiz, Belén, Cano-Cortés, Victoria, Cruz-López, Olga, Gonzalez-Resines, Saúl, Domene, Carmen, Conejo-García, Ana, Sánchez-Martín, Rosario M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032636/ https://www.ncbi.nlm.nih.gov/pubmed/35456622 http://dx.doi.org/10.3390/pharmaceutics14040788 |
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