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Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents
Conformationally restrained polyamine analog PG11047 is a well-known drug candidate that modulates polyamine metabolism and inhibits cancer cell growth in a broad spectrum of cancers. Here, we report a structure–activity relationship study of the PG11047 analogs (HPGs) containing alkyl chains of var...
Autores principales: | Sil, Diptesh, Panja, Sudipta, Jogdeo, Chinmay M., Kumar, Raj, Yu, Ao, Holbert, Cassandra E., Ding, Ling, Foley, Jackson R., Stewart, Tracy Murray, Casero, Robert A., Oupický, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032695/ https://www.ncbi.nlm.nih.gov/pubmed/35458639 http://dx.doi.org/10.3390/molecules27082441 |
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