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Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data

Background: Machine Learning (ML) in arthroplasty is becoming more popular, as it is perfectly suited for prediction models. However, results have been heterogeneous so far. We hypothesize that an accurate ML model for outcome prediction in THA must be able to compute arthroplasty-specific data. In...

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Autores principales: Lazic, Igor, Hinterwimmer, Florian, Langer, Severin, Pohlig, Florian, Suren, Christian, Seidl, Fritz, Rückert, Daniel, Burgkart, Rainer, von Eisenhart-Rothe, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032696/
https://www.ncbi.nlm.nih.gov/pubmed/35456239
http://dx.doi.org/10.3390/jcm11082147
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author Lazic, Igor
Hinterwimmer, Florian
Langer, Severin
Pohlig, Florian
Suren, Christian
Seidl, Fritz
Rückert, Daniel
Burgkart, Rainer
von Eisenhart-Rothe, Rüdiger
author_facet Lazic, Igor
Hinterwimmer, Florian
Langer, Severin
Pohlig, Florian
Suren, Christian
Seidl, Fritz
Rückert, Daniel
Burgkart, Rainer
von Eisenhart-Rothe, Rüdiger
author_sort Lazic, Igor
collection PubMed
description Background: Machine Learning (ML) in arthroplasty is becoming more popular, as it is perfectly suited for prediction models. However, results have been heterogeneous so far. We hypothesize that an accurate ML model for outcome prediction in THA must be able to compute arthroplasty-specific data. In this study, we evaluate a ML approach applying data from two German arthroplasty-specific registries to predict adverse outcomes after THA, after careful evaluations of ML algorithms, outcome and input variables by an interdisciplinary team of data scientists and surgeons. Methods: Data of 1217 cases of primary THA from a single center were derived from two German arthroplasty-specific registries between 2016 to 2019. The XGBoost algorithm was adjusted and applied. Accuracy, sensitivity, specificity and AUC were calculated. Results: For the prediction of complications, the ML algorithm achieved an accuracy of 80.3%, a sensitivity of 31.0%, a specificity of 89.4% and an AUC of 64.1%. For the prediction of surgery duration, the ML algorithm yielded an accuracy of 81.7%, a sensitivity of 58.2%, a specificity of 91.6% and an AUC of 89.1%. The feature importance indicated non-linear outcomes for age, height, weight and surgeon. No relevant linear correlations were found. Conclusion: The attunement of input and output data as well as the modifications of the ML algorithm permitted the development of a feasible ML model for the prediction of complications and surgery duration.
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spelling pubmed-90326962022-04-23 Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data Lazic, Igor Hinterwimmer, Florian Langer, Severin Pohlig, Florian Suren, Christian Seidl, Fritz Rückert, Daniel Burgkart, Rainer von Eisenhart-Rothe, Rüdiger J Clin Med Article Background: Machine Learning (ML) in arthroplasty is becoming more popular, as it is perfectly suited for prediction models. However, results have been heterogeneous so far. We hypothesize that an accurate ML model for outcome prediction in THA must be able to compute arthroplasty-specific data. In this study, we evaluate a ML approach applying data from two German arthroplasty-specific registries to predict adverse outcomes after THA, after careful evaluations of ML algorithms, outcome and input variables by an interdisciplinary team of data scientists and surgeons. Methods: Data of 1217 cases of primary THA from a single center were derived from two German arthroplasty-specific registries between 2016 to 2019. The XGBoost algorithm was adjusted and applied. Accuracy, sensitivity, specificity and AUC were calculated. Results: For the prediction of complications, the ML algorithm achieved an accuracy of 80.3%, a sensitivity of 31.0%, a specificity of 89.4% and an AUC of 64.1%. For the prediction of surgery duration, the ML algorithm yielded an accuracy of 81.7%, a sensitivity of 58.2%, a specificity of 91.6% and an AUC of 89.1%. The feature importance indicated non-linear outcomes for age, height, weight and surgeon. No relevant linear correlations were found. Conclusion: The attunement of input and output data as well as the modifications of the ML algorithm permitted the development of a feasible ML model for the prediction of complications and surgery duration. MDPI 2022-04-12 /pmc/articles/PMC9032696/ /pubmed/35456239 http://dx.doi.org/10.3390/jcm11082147 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lazic, Igor
Hinterwimmer, Florian
Langer, Severin
Pohlig, Florian
Suren, Christian
Seidl, Fritz
Rückert, Daniel
Burgkart, Rainer
von Eisenhart-Rothe, Rüdiger
Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data
title Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data
title_full Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data
title_fullStr Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data
title_full_unstemmed Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data
title_short Prediction of Complications and Surgery Duration in Primary Total Hip Arthroplasty Using Machine Learning: The Necessity of Modified Algorithms and Specific Data
title_sort prediction of complications and surgery duration in primary total hip arthroplasty using machine learning: the necessity of modified algorithms and specific data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032696/
https://www.ncbi.nlm.nih.gov/pubmed/35456239
http://dx.doi.org/10.3390/jcm11082147
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