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Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m(6)A Methylation of RNA in Acute Myeloid Leukemia Cells

N(6)A-methyladenosine (m(6)A) post-transcriptional modification, the most abundant internal RNA modification, is catalyzed by the METTL3-14 methyltransferase complex. Recently, attention has been drawn to the METTL3-14 complex regarding its significant roles in the pathogenesis of acute myeloid leuk...

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Detalles Bibliográficos
Autores principales:	Lee, Je-Heon, Choi, Namjeong, Kim, Subin, Jin, Mi Sun, Shen, Haihong, Kim, Yong-Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032718/ https://www.ncbi.nlm.nih.gov/pubmed/35455436 http://dx.doi.org/10.3390/ph15040440

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