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Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection

Carbon dots (CDs) can be prepared from various organic (abundant) compounds that are rich in surfaces with –OH, –COOH, and –NH(2) groups. Therefore, CDs exhibit good biocompatibility and electron transfer ability, allowing flexible surface modification and accelerated electron transfer during cataly...

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Autores principales: Xie, Yuqi, Ma, Lu, Ling, Shaoming, Ouyang, Huixiang, Liang, Aihui, Jiang, Zhiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032719/
https://www.ncbi.nlm.nih.gov/pubmed/35458083
http://dx.doi.org/10.3390/nano12081374
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author Xie, Yuqi
Ma, Lu
Ling, Shaoming
Ouyang, Huixiang
Liang, Aihui
Jiang, Zhiliang
author_facet Xie, Yuqi
Ma, Lu
Ling, Shaoming
Ouyang, Huixiang
Liang, Aihui
Jiang, Zhiliang
author_sort Xie, Yuqi
collection PubMed
description Carbon dots (CDs) can be prepared from various organic (abundant) compounds that are rich in surfaces with –OH, –COOH, and –NH(2) groups. Therefore, CDs exhibit good biocompatibility and electron transfer ability, allowing flexible surface modification and accelerated electron transfer during catalysis. Herein, CDs were prepared using a hydrothermal method with fructose, saccharose, and citric acid as C sources and urea as an N dopant. The as-prepared CDs were used to catalyze AgNO(3)–trisodium citrate (TSC) to produce Ag nanoparticles (AgNPs). The surface-enhanced Raman scattering (SERS) intensity increased with the increasing CDs concentration with Victoria blue B (VBB) as a signal molecule. The CDs exhibited a strong catalytic activity, with the highest activity shown by fructose-based CDs. After N doping, catalytic performance improved; with the passivation of a wrapped aptamer, the electron transfer was effectively disrupted (retarded). This resulted in the inhibition of the reaction and a decrease in the SERS intensity. When bisphenol A (BPA) was added, it specifically bound to the aptamer and CDs were released, recovering catalytical activity. The SERS intensity increased with BPA over the concentration range of 0.33–66.67 nmol/L. Thus, the aptamer-adjusted nanocatalytic SERS method can be applied for BPA detection.
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spelling pubmed-90327192022-04-23 Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection Xie, Yuqi Ma, Lu Ling, Shaoming Ouyang, Huixiang Liang, Aihui Jiang, Zhiliang Nanomaterials (Basel) Article Carbon dots (CDs) can be prepared from various organic (abundant) compounds that are rich in surfaces with –OH, –COOH, and –NH(2) groups. Therefore, CDs exhibit good biocompatibility and electron transfer ability, allowing flexible surface modification and accelerated electron transfer during catalysis. Herein, CDs were prepared using a hydrothermal method with fructose, saccharose, and citric acid as C sources and urea as an N dopant. The as-prepared CDs were used to catalyze AgNO(3)–trisodium citrate (TSC) to produce Ag nanoparticles (AgNPs). The surface-enhanced Raman scattering (SERS) intensity increased with the increasing CDs concentration with Victoria blue B (VBB) as a signal molecule. The CDs exhibited a strong catalytic activity, with the highest activity shown by fructose-based CDs. After N doping, catalytic performance improved; with the passivation of a wrapped aptamer, the electron transfer was effectively disrupted (retarded). This resulted in the inhibition of the reaction and a decrease in the SERS intensity. When bisphenol A (BPA) was added, it specifically bound to the aptamer and CDs were released, recovering catalytical activity. The SERS intensity increased with BPA over the concentration range of 0.33–66.67 nmol/L. Thus, the aptamer-adjusted nanocatalytic SERS method can be applied for BPA detection. MDPI 2022-04-17 /pmc/articles/PMC9032719/ /pubmed/35458083 http://dx.doi.org/10.3390/nano12081374 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Xie, Yuqi
Ma, Lu
Ling, Shaoming
Ouyang, Huixiang
Liang, Aihui
Jiang, Zhiliang
Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection
title Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection
title_full Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection
title_fullStr Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection
title_full_unstemmed Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection
title_short Aptamer-Adjusted Carbon Dot Catalysis-Silver Nanosol SERS Spectrometry for Bisphenol A Detection
title_sort aptamer-adjusted carbon dot catalysis-silver nanosol sers spectrometry for bisphenol a detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032719/
https://www.ncbi.nlm.nih.gov/pubmed/35458083
http://dx.doi.org/10.3390/nano12081374
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