Cargando…

Oestrogen Receptor Isoforms May Represent a Therapeutic Target in Oesophageal Adenocarcinoma

SIMPLE SUMMARY: Oesophageal adenocarcinoma is a lethal malignancy with limited treatment options. Recent studies have identified oestrogen receptors (ERs) in this cancer, which could represent a new target for therapy. In this study, we used laboratory models of oesophageal adenocarcinoma to look fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Due, Steven L., Watson, David I., Bastian, Isabell, Eichelmann, Ann-Kathrin, Hussey, Damian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032750/ https://www.ncbi.nlm.nih.gov/pubmed/35454796 http://dx.doi.org/10.3390/cancers14081891

Ejemplares similares

Mutant p53 Mediates Sensitivity to Cancer Treatment Agents in Oesophageal Adenocarcinoma Associated with MicroRNA and SLC7A11 Expression
por: Eichelmann, Ann-Kathrin, et al.
Publicado: (2021)

MicroRNA Profiling in Oesophageal Adenocarcinoma Cell Lines and Patient Serum Samples Reveals a Role for miR-451a in Radiation Resistance
por: Butz, Frederike, et al.
Publicado: (2020)

Probing the link between oestrogen receptors and oesophageal cancer
por: Rashid, Farhan, et al.
Publicado: (2010)

Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro
por: Al-Khyatt, Waleed, et al.
Publicado: (2018)

Differential regulation of oestrogen receptor β isoforms by 5′ untranslated regions in cancer
por: Smith, Laura, et al.
Publicado: (2010)

Classical oestrogen receptor is not detectable in pancreatic adenocarcinoma.
por: Taylor, O. M., et al.
Publicado: (1992)

Complex Epigenetic Regulation of Chemotherapy Resistance and Biology in Esophageal Squamous Cell Carcinoma via MicroRNAs
por: Lindner, Kirsten, et al.
Publicado: (2018)

Correction: Complex Epigenetic Regulation of Chemotherapy Resistance and Biology in Esophageal Squamous Cell Carcinoma via MicroRNAs. Int. J. Mol. Sci. 2018, 19, 499
por: Lindner, Kirsten, et al.
Publicado: (2019)

Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer
por: Murphy, L C, et al.
Publicado: (2002)

Oestrogen receptor isoforms, their distribution and relation to progesterone receptor levels in breast cancer samples.
por: Baker, V. A., et al.
Publicado: (1992)

Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett’s Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium
por: Lagergren, Katarina, et al.
Publicado: (2015)

Expression of oestrogen receptor-β in oestrogen receptor-α negative human breast tumours
por: Skliris, G P, et al.
Publicado: (2006)

Oestrogens and oestrogen receptors in prostate cancer
por: Kowalska, Karolina, et al.
Publicado: (2016)

Oestrogen receptor protein and mRNA in adenocarcinoma of the uterine cervix.
por: Ismail, S. M., et al.
Publicado: (1992)

Computational modelling suggests that Barrett’s oesophagus may be the precursor of all oesophageal adenocarcinomas
por: Curtius, Kit, et al.
Publicado: (2021)

Histone Modifying Enzymes as Targets for Therapeutic Intervention in Oesophageal Adenocarcinoma
por: Pickering, Oliver J., et al.
Publicado: (2021)

Impact of gastro-oesophageal reflux on microRNA expression, location and function
por: Smith, Cameron M, et al.
Publicado: (2013)

Of Oestrogens and Sperm: A Review of the Roles of Oestrogens and Oestrogen Receptors in Male Reproduction
por: Dostalova, Pavla, et al.
Publicado: (2017)

Plasma oestrogens and oestrogen receptors in breast cancer patients.
por: Mason, R. C., et al.
Publicado: (1985)

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma
por: Gotovac, Jovana R, et al.
Publicado: (2020)

Tonsillar metastasis of oesophageal adenocarcinoma
por: Struijs, Bram, et al.
Publicado: (2007)

MicroRNA-196a & microRNA-101 expression in Barrett's oesophagus in patients with medically and surgically treated gastro-oesophageal reflux
por: Haiart, Sebastien, et al.
Publicado: (2011)

Oestrogen receptor-mediated expression of Olfactomedin 4 regulates the progression of endometrial adenocarcinoma
por: Duan, Chao, et al.
Publicado: (2014)

Oestrogen receptor alpha in pulmonary hypertension
por: Wright, Audrey F., et al.
Publicado: (2015)

Spontaneous and inducible apoptosis in oesophageal adenocarcinoma
por: Raouf, A, et al.
Publicado: (2001)

The future of combination immunotherapy in oesophageal adenocarcinoma
por: Davern, Maria, et al.
Publicado: (2023)

The Evolution of Neo-Adjuvant Therapy in the Treatment of Oesophageal and Gastro-Oesophageal Junction Adenocarcinomas
por: Dermanis, Alexander A., et al.
Publicado: (2023)

Bile acids influence the growth, oestrogen receptor and oestrogen-regulated proteins of MCF-7 human breast cancer cells.
por: Baker, P. R., et al.
Publicado: (1992)

Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma
por: Mongan, Ann Marie, et al.
Publicado: (2019)

Different methylation of oestrogen receptor DNA in human breast carcinomas with and without oestrogen receptor.
por: Piva, R., et al.
Publicado: (1990)

Oesophageal artefact may significantly affect oesophageal pressure measurement in mechanically ventilated patients
por: Mojoli, F, et al.
Publicado: (2015)

High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers
por: Brimmell, M, et al.
Publicado: (1999)

Oestrogen receptor beta isoform expression in sporadic colorectal cancer, familial adenomatous polyposis and progressive stages of colorectal cancer
por: Stevanato Filho, Paulo Roberto, et al.
Publicado: (2017)

Profiling the expression and function of oestrogen receptor isoform ER46 in human endometrial tissues and uterine natural killer cells
por: Gibson, Douglas A, et al.
Publicado: (2020)

Alternative promoters and splicing create multiple functionally distinct isoforms of oestrogen receptor alpha in breast cancer and healthy tissues
por: Balcazar Lopez, Carlos Enrique, et al.
Publicado: (2023)

Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation
por: Gellert, Pascal, et al.
Publicado: (2016)

Vitamin D receptor as a marker of prognosis in oesophageal adenocarcinoma: a prospective cohort study
por: McCain, Stephen, et al.
Publicado: (2018)

Glucose transporter 1 expression as a marker of prognosis in oesophageal adenocarcinoma
por: Blayney, Jaine K., et al.
Publicado: (2018)

Oestrogen and androgen receptors in melanoma.
por: Rümke, P., et al.
Publicado: (1980)

Odontoid peg metastasis from an oesophageal adenocarcinoma.
por: Walsh, I. K., et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_2g41tjr4u1rkvje3i3edpnj7ol