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Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose

To develop a method of estimating surface dose in whole breast irradiation, we used an anthropomorphic phantom with accessories for the simulation of different breast sizes. The surface points, which are measured by TLDs, are set along with two main directions, superior-inferior and medial-lateral....

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Autores principales: Yen, Tsung-Yu, Chuang, Kai-Cheng, Fu, Hsiao-Mei, Feng, Chen-Ju, Lien, Ke-Yu, Hsu, Shih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032752/
https://www.ncbi.nlm.nih.gov/pubmed/35456253
http://dx.doi.org/10.3390/jcm11082154
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author Yen, Tsung-Yu
Chuang, Kai-Cheng
Fu, Hsiao-Mei
Feng, Chen-Ju
Lien, Ke-Yu
Hsu, Shih-Ming
author_facet Yen, Tsung-Yu
Chuang, Kai-Cheng
Fu, Hsiao-Mei
Feng, Chen-Ju
Lien, Ke-Yu
Hsu, Shih-Ming
author_sort Yen, Tsung-Yu
collection PubMed
description To develop a method of estimating surface dose in whole breast irradiation, we used an anthropomorphic phantom with accessories for the simulation of different breast sizes. The surface points, which are measured by TLDs, are set along with two main directions, superior-inferior and medial-lateral. The incident angle between the photon beam and the surface and the doses at 1 cm beneath the surface at every point are assessed by a computerized treatment planning system (cTPS). With the prescription dose of 200 cGy, the average surface doses under tangential irradiation are 97.73 (±14.96) cGy, 99.90 (±10.73) cGy, and 105.26 (±9.21) cGy for large, medium, and small breast volumes, respectively. The surface dose increased in the model of small breast volume without significance (p = 0.39). The linear analysis between surface dose and the incident angle is y = 0.5258x + 69.648, R(2) = 0.7131 (x: incident angle and y: surface dose). We develop the percentage of skin surface dose with reference to a depth of 1 cm (PSDR1cm) to normalize the inhomogeneous dose. The relationship between incident angle and PSDR1cm is y = 0.1894x + 36.021, R(2) = 0.6536 (x: incident angle and y: PSDR1cm) by linear analysis. In conclusion, the surface dose in whole breast irradiation could be estimated from this linear relationship between PSDR1cm and incident angle in daily clinical practice by cTPS. Further in vivo data should be studied to verify this formula.
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spelling pubmed-90327522022-04-23 Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose Yen, Tsung-Yu Chuang, Kai-Cheng Fu, Hsiao-Mei Feng, Chen-Ju Lien, Ke-Yu Hsu, Shih-Ming J Clin Med Article To develop a method of estimating surface dose in whole breast irradiation, we used an anthropomorphic phantom with accessories for the simulation of different breast sizes. The surface points, which are measured by TLDs, are set along with two main directions, superior-inferior and medial-lateral. The incident angle between the photon beam and the surface and the doses at 1 cm beneath the surface at every point are assessed by a computerized treatment planning system (cTPS). With the prescription dose of 200 cGy, the average surface doses under tangential irradiation are 97.73 (±14.96) cGy, 99.90 (±10.73) cGy, and 105.26 (±9.21) cGy for large, medium, and small breast volumes, respectively. The surface dose increased in the model of small breast volume without significance (p = 0.39). The linear analysis between surface dose and the incident angle is y = 0.5258x + 69.648, R(2) = 0.7131 (x: incident angle and y: surface dose). We develop the percentage of skin surface dose with reference to a depth of 1 cm (PSDR1cm) to normalize the inhomogeneous dose. The relationship between incident angle and PSDR1cm is y = 0.1894x + 36.021, R(2) = 0.6536 (x: incident angle and y: PSDR1cm) by linear analysis. In conclusion, the surface dose in whole breast irradiation could be estimated from this linear relationship between PSDR1cm and incident angle in daily clinical practice by cTPS. Further in vivo data should be studied to verify this formula. MDPI 2022-04-12 /pmc/articles/PMC9032752/ /pubmed/35456253 http://dx.doi.org/10.3390/jcm11082154 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yen, Tsung-Yu
Chuang, Kai-Cheng
Fu, Hsiao-Mei
Feng, Chen-Ju
Lien, Ke-Yu
Hsu, Shih-Ming
Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose
title Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose
title_full Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose
title_fullStr Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose
title_full_unstemmed Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose
title_short Estimation of the Surface Dose in Breast Irradiation by the Beam Incident Angle and the 1 cm Depth Dose
title_sort estimation of the surface dose in breast irradiation by the beam incident angle and the 1 cm depth dose
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032752/
https://www.ncbi.nlm.nih.gov/pubmed/35456253
http://dx.doi.org/10.3390/jcm11082154
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