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Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?

Genetic variants of severe acute respiratory syndrome coronavirus (SARS-CoV-2) have been globally surging and devastating many countries around the world. There are at least eleven reported variants dedicated with inevitably catastrophic consequences. In 2021, the most dominant Delta and Omicron var...

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Autores principales: Duong, Bao V., Larpruenrudee, Puchanee, Fang, Tianxin, Hossain, Sheikh I., Saha, Suvash C., Gu, Yuantong, Islam, Mohammad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032753/
https://www.ncbi.nlm.nih.gov/pubmed/35457468
http://dx.doi.org/10.3390/ijerph19084586
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author Duong, Bao V.
Larpruenrudee, Puchanee
Fang, Tianxin
Hossain, Sheikh I.
Saha, Suvash C.
Gu, Yuantong
Islam, Mohammad S.
author_facet Duong, Bao V.
Larpruenrudee, Puchanee
Fang, Tianxin
Hossain, Sheikh I.
Saha, Suvash C.
Gu, Yuantong
Islam, Mohammad S.
author_sort Duong, Bao V.
collection PubMed
description Genetic variants of severe acute respiratory syndrome coronavirus (SARS-CoV-2) have been globally surging and devastating many countries around the world. There are at least eleven reported variants dedicated with inevitably catastrophic consequences. In 2021, the most dominant Delta and Omicron variants were estimated to lead to more severity and deaths than other variants. Furthermore, these variants have some contagious characteristics involving high transmissibility, more severe illness, and an increased mortality rate. All outbreaks caused by the Delta variant have been rapidly skyrocketing in infection cases in communities despite tough restrictions in 2021. Apart from it, the United States, the United Kingdom and other high-rate vaccination rollout countries are still wrestling with this trend because the Delta variant can result in a significant number of breakthrough infections. However, the pandemic has changed since the latest SARS-CoV-2 variant in late 2021 in South Africa, Omicron. The preliminary data suggest that the Omicron variant possesses 100-fold greater than the Delta variant in transmissibility. Therefore, this paper aims to review these characteristics based on the available meta-data and information from the first emergence to recent days. Australia and the five most affected countries, including the United States, India, Brazil, France, as well as the United Kingdom, are selected in order to review the transmissibility, severity and fatality due to Delta and Omicron variants. Finally, the vaccination programs for each country are also reviewed as the main factor in prevention.
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spelling pubmed-90327532022-04-23 Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant? Duong, Bao V. Larpruenrudee, Puchanee Fang, Tianxin Hossain, Sheikh I. Saha, Suvash C. Gu, Yuantong Islam, Mohammad S. Int J Environ Res Public Health Review Genetic variants of severe acute respiratory syndrome coronavirus (SARS-CoV-2) have been globally surging and devastating many countries around the world. There are at least eleven reported variants dedicated with inevitably catastrophic consequences. In 2021, the most dominant Delta and Omicron variants were estimated to lead to more severity and deaths than other variants. Furthermore, these variants have some contagious characteristics involving high transmissibility, more severe illness, and an increased mortality rate. All outbreaks caused by the Delta variant have been rapidly skyrocketing in infection cases in communities despite tough restrictions in 2021. Apart from it, the United States, the United Kingdom and other high-rate vaccination rollout countries are still wrestling with this trend because the Delta variant can result in a significant number of breakthrough infections. However, the pandemic has changed since the latest SARS-CoV-2 variant in late 2021 in South Africa, Omicron. The preliminary data suggest that the Omicron variant possesses 100-fold greater than the Delta variant in transmissibility. Therefore, this paper aims to review these characteristics based on the available meta-data and information from the first emergence to recent days. Australia and the five most affected countries, including the United States, India, Brazil, France, as well as the United Kingdom, are selected in order to review the transmissibility, severity and fatality due to Delta and Omicron variants. Finally, the vaccination programs for each country are also reviewed as the main factor in prevention. MDPI 2022-04-11 /pmc/articles/PMC9032753/ /pubmed/35457468 http://dx.doi.org/10.3390/ijerph19084586 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Duong, Bao V.
Larpruenrudee, Puchanee
Fang, Tianxin
Hossain, Sheikh I.
Saha, Suvash C.
Gu, Yuantong
Islam, Mohammad S.
Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
title Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
title_full Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
title_fullStr Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
title_full_unstemmed Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
title_short Is the SARS CoV-2 Omicron Variant Deadlier and More Transmissible Than Delta Variant?
title_sort is the sars cov-2 omicron variant deadlier and more transmissible than delta variant?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032753/
https://www.ncbi.nlm.nih.gov/pubmed/35457468
http://dx.doi.org/10.3390/ijerph19084586
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