Cargando…

Histone Demethylase KDM5C Drives Prostate Cancer Progression by Promoting EMT

SIMPLE SUMMARY: Prostate cancer is the most common cancer in men and is one of the leading causes of cancer-related deaths. During prostate cancer progression and metastasis, the epithelial cells can undergo epithelial–mesenchymal transition (EMT). Here, we show that the histone demethylase KDM5C is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lemster, Anna-Lena, Sievers, Elisabeth, Pasternack, Helen, Lazar-Karsten, Pamela, Klümper, Niklas, Sailer, Verena, Offermann, Anne, Brägelmann, Johannes, Perner, Sven, Kirfel, Jutta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032772/ https://www.ncbi.nlm.nih.gov/pubmed/35454801 http://dx.doi.org/10.3390/cancers14081894

Ejemplares similares

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila
por: Drelon, Coralie, et al.
Publicado: (2018)

The nuclear bodies formed by histone demethylase KDM7A
por: Ming, Hui, et al.
Publicado: (2020)

Histone demethylase KDM4C is a functional dependency in JAK2-mutated neoplasms
por: Ernst, Philipp, et al.
Publicado: (2022)

The histone demethylase Kdm3a is essential to progression through differentiation
por: Herzog, Marielle, et al.
Publicado: (2012)

Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
por: Leurs, Ulrike, et al.
Publicado: (2014)

Histone demethylase KDM5A promotes tumorigenesis of osteosarcoma tumor
por: Peng, Daohu, et al.
Publicado: (2021)

Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase
por: Lee, Su-Hyun, et al.
Publicado: (2021)

Elevated LSD1 and SNAIL Expression Indicate Poor Prognosis in Hypopharynx Carcinoma
por: Bottner, Justus, et al.
Publicado: (2022)

ETS transcription factor ERG cooperates with histone demethylase KDM4A
por: KIM, TAE-DONG, et al.
Publicado: (2016)

Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases
por: Ambrosio, Susanna, et al.
Publicado: (2018)

Human histone demethylase KDM6B can catalyse sequential oxidations
por: Hopkinson, Richard J., et al.
Publicado: (2018)

KDM5 histone demethylases repress immune response via suppression of STING
por: Wu, Lizhen, et al.
Publicado: (2018)

Molecular architecture of the Jumonji C family histone demethylase KDM5B
por: Dorosz, Jerzy, et al.
Publicado: (2019)

The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer
por: Wilson, C, et al.
Publicado: (2017)

Proteomics based identification of KDM5 histone demethylases associated with cardiovascular disease
por: Mokou, Marika, et al.
Publicado: (2019)

Advances in Histone Demethylase KDM3A as a Cancer Therapeutic Target
por: Yoo, Jung, et al.
Publicado: (2020)

Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy
por: Jose, Anmi, et al.
Publicado: (2020)

Structure‐Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases
por: Małecki, Piotr H., et al.
Publicado: (2019)

In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation
por: Krupar, Rosemarie, et al.
Publicado: (2020)

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells
por: Wu, Liangtang, et al.
Publicado: (2015)

Targeting of Histone Demethylases KDM5A and KDM6B Inhibits the Proliferation of Temozolomide-Resistant Glioblastoma Cells
por: Romani, Massimo, et al.
Publicado: (2019)

Histone Lysine Demethylases KDM5B and KDM5C Modulate Genome Activation and Stability in Porcine Embryos
por: Glanzner, Werner Giehl, et al.
Publicado: (2020)

KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance
por: Gaillard, Solenne, et al.
Publicado: (2021)

Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis
por: Yoo, Jung, et al.
Publicado: (2022)

Female Bias in Rhox6 and 9 Regulation by the Histone Demethylase KDM6A
por: Berletch, Joel B., et al.
Publicado: (2013)

The histone demethylase LSD1/KDM1A promotes the DNA damage response
por: Mosammaparast, Nima, et al.
Publicado: (2013)

Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates
por: Tarhonskaya, Hanna, et al.
Publicado: (2017)

Hypoxia and Hormone-Mediated Pathways Converge at the Histone Demethylase KDM4B in Cancer
por: Yang, Jun, et al.
Publicado: (2018)

KDM5A demethylase: Erasing histone modifications to promote repair of DNA breaks
por: Price, Brendan D.
Publicado: (2017)

Histone Demethylase KDM4C Is Required for Ovarian Cancer Stem Cell Maintenance
por: Chen, Guo-Qing, et al.
Publicado: (2020)

The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
por: Belalcazar, Helen M., et al.
Publicado: (2021)

The Diverse Roles of Histone Demethylase KDM4B in Normal and Cancer Development and Progression
por: Wang, Zhongze, et al.
Publicado: (2022)

Sexually Dimorphic Alterations in the Transcriptome and Behavior with Loss of Histone Demethylase KDM5C
por: Bonefas, Katherine M., et al.
Publicado: (2023)

The histone demethylase Kdm3 prevents auto-immune piRNAs production in Drosophila
por: Casier, Karine, et al.
Publicado: (2023)

TACH101, a first-in-class pan-inhibitor of KDM4 histone demethylase
por: Chandhasin, Chandtip, et al.
Publicado: (2023)

Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family
por: Lal, Sneha, et al.
Publicado: (2018)

Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family
por: Hillringhaus, Lars, et al.
Publicado: (2011)

How substrate specificity is imposed on a histone demethylase—lessons from KDM2A
por: Tsai, Chi-Lin, et al.
Publicado: (2014)

Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling
por: Tsurumi, Amy, et al.
Publicado: (2013)

The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma
por: Pajtler, Kristian W, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_voi6huopef3aa1t98v7jm260i9