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Application of mTORC1 Inhibitors for Tissue-Agnostic Management of Standard-Therapy-Refractory Solid Tumors
SIMPLE SUMMARY: Hyperactivation of the mTOR pathway is a common occurrence in malignancies. This study investigated the clinical benefit of the tissue-agnostic application of mTOR inhibitors for the therapeutic management of a pan-cancer cohort of patients with mTOR pathway aberrations. Seventy-one...
Autores principales: | Taghizadeh, Hossein, Maj-Hes, Agnieszka, Prager, Gerald W., Müllauer, Leonhard, Mader, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032789/ https://www.ncbi.nlm.nih.gov/pubmed/35454843 http://dx.doi.org/10.3390/cancers14081936 |
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