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Structural basis for C-type inactivation in a Shaker family voltage-gated K(+) channel

C-type inactivation is a process by which ion flux through a voltage-gated K(+) (K(v)) channel is regulated at the selectivity filter. While prior studies have indicated that C-type inactivation involves structural changes at the selectivity filter, the nature of the changes has not been resolved. H...

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Detalles Bibliográficos
Autores principales: Reddi, Ravikumar, Matulef, Kimberly, Riederer, Erika A., Whorton, Matthew R., Valiyaveetil, Francis I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032944/
https://www.ncbi.nlm.nih.gov/pubmed/35452285
http://dx.doi.org/10.1126/sciadv.abm8804

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