Development of Robust Varicella Zoster Virus Luciferase Reporter Viruses for In Vivo Monitoring of Virus Growth and Its Antiviral Inhibition in Culture, Skin, and Humanized Mice

There is a continued need to understand varicella-zoster virus (VZV) pathogenesis and to develop more effective antivirals, as it causes chickenpox and zoster. As a human-restricted alphaherpesvirus, the use of human skin in culture and mice is critical in order to reveal the important VZV genes tha...

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Detalles Bibliográficos
Autores principales: Lloyd, Megan G., Yee, Michael B., Flot, Joseph S., Liu, Dongmei, Geiler, Brittany W., Kinchington, Paul R., Moffat, Jennifer F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032946/
https://www.ncbi.nlm.nih.gov/pubmed/35458556
http://dx.doi.org/10.3390/v14040826

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