Improved Atrial Differentiation of Human Pluripotent Stem Cells by Activation of Retinoic Acid Receptor Alpha (RARα)

Human pluripotent stem cell (hPSC)-derived cardiomyocytes have proven valuable for modeling disease and as a drug screening platform. Here, we depict an optimized protocol for the directed differentiation of hPSCs toward cardiomyocytes with an atrial identity by modulating the retinoic acid signalin...

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Detalles Bibliográficos
Autores principales: Schwach, Verena, Cofiño-Fabres, Carla, ten Den, Simone A., Passier, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032956/
https://www.ncbi.nlm.nih.gov/pubmed/35455744
http://dx.doi.org/10.3390/jpm12040628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032956/
https://www.ncbi.nlm.nih.gov/pubmed/35455744
http://dx.doi.org/10.3390/jpm12040628

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