Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites

The misuse of many types of broad-spectrum antibiotics leads to increased antimicrobial resistance. As a result, the development of a novel antibacterial agent is essential. Photodynamic antimicrobial chemotherapy (PACT) is becoming more popular due to its advantages in eliminating drug-resistant st...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyan, Abbas, Khurram, Yang, Yuxiang, Li, Zijian, Tedesco, Antonio Claudio, Bi, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032997/
https://www.ncbi.nlm.nih.gov/pubmed/35455484
http://dx.doi.org/10.3390/ph15040487
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author Wu, Xiaoyan
Abbas, Khurram
Yang, Yuxiang
Li, Zijian
Tedesco, Antonio Claudio
Bi, Hong
author_facet Wu, Xiaoyan
Abbas, Khurram
Yang, Yuxiang
Li, Zijian
Tedesco, Antonio Claudio
Bi, Hong
author_sort Wu, Xiaoyan
collection PubMed
description The misuse of many types of broad-spectrum antibiotics leads to increased antimicrobial resistance. As a result, the development of a novel antibacterial agent is essential. Photodynamic antimicrobial chemotherapy (PACT) is becoming more popular due to its advantages in eliminating drug-resistant strains and providing broad-spectrum antibacterial resistance. Carbon dots (CDs), zero-dimensional nanomaterials with diameters smaller than 10 nm, offer a green and cost-effective alternative to PACT photosensitizers. This article reviewed the synthesis methods of antibacterial CDs as well as the recent progress of CDs and their nanocomposites in photodynamic sterilization, focusing on maximizing the bactericidal impact of CDs photosensitizers. This review establishes the base for future CDs development in the PACT field.
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spelling pubmed-90329972022-04-23 Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites Wu, Xiaoyan Abbas, Khurram Yang, Yuxiang Li, Zijian Tedesco, Antonio Claudio Bi, Hong Pharmaceuticals (Basel) Review The misuse of many types of broad-spectrum antibiotics leads to increased antimicrobial resistance. As a result, the development of a novel antibacterial agent is essential. Photodynamic antimicrobial chemotherapy (PACT) is becoming more popular due to its advantages in eliminating drug-resistant strains and providing broad-spectrum antibacterial resistance. Carbon dots (CDs), zero-dimensional nanomaterials with diameters smaller than 10 nm, offer a green and cost-effective alternative to PACT photosensitizers. This article reviewed the synthesis methods of antibacterial CDs as well as the recent progress of CDs and their nanocomposites in photodynamic sterilization, focusing on maximizing the bactericidal impact of CDs photosensitizers. This review establishes the base for future CDs development in the PACT field. MDPI 2022-04-18 /pmc/articles/PMC9032997/ /pubmed/35455484 http://dx.doi.org/10.3390/ph15040487 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wu, Xiaoyan
Abbas, Khurram
Yang, Yuxiang
Li, Zijian
Tedesco, Antonio Claudio
Bi, Hong
Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites
title Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites
title_full Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites
title_fullStr Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites
title_full_unstemmed Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites
title_short Photodynamic Anti-Bacteria by Carbon Dots and Their Nano-Composites
title_sort photodynamic anti-bacteria by carbon dots and their nano-composites
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032997/
https://www.ncbi.nlm.nih.gov/pubmed/35455484
http://dx.doi.org/10.3390/ph15040487
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