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Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report

Numerous data indicate the presence of cognitive impairment in people who have undergone COVID-19, often called COVID Fog (CF). This phenomenon persists even 6 months after infection, and its etiology and pathogenesis are not fully known. The aim of this article was to analyze the relationship among...

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Autores principales: Klimkiewicz, Jakub, Pankowski, Daniel, Wytrychiewicz-Pankowska, Kinga, Klimkiewicz, Anna, Siwik, Paulina, Klimczuk, Joanna, Lubas, Arkadiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033019/
https://www.ncbi.nlm.nih.gov/pubmed/35458142
http://dx.doi.org/10.3390/nu14081580
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author Klimkiewicz, Jakub
Pankowski, Daniel
Wytrychiewicz-Pankowska, Kinga
Klimkiewicz, Anna
Siwik, Paulina
Klimczuk, Joanna
Lubas, Arkadiusz
author_facet Klimkiewicz, Jakub
Pankowski, Daniel
Wytrychiewicz-Pankowska, Kinga
Klimkiewicz, Anna
Siwik, Paulina
Klimczuk, Joanna
Lubas, Arkadiusz
author_sort Klimkiewicz, Jakub
collection PubMed
description Numerous data indicate the presence of cognitive impairment in people who have undergone COVID-19, often called COVID Fog (CF). This phenomenon persists even 6 months after infection, and its etiology and pathogenesis are not fully known. The aim of this article was to analyze the relationship among cognitive functioning, clinical data and nutrition indexes in patients discharged from the COVID-19 hospital of the Military Institute of Medicine, Warsaw, Poland. The sample comprised 17 individuals—10 women and 7 men, with ages of 65 ± 14 years. Cognitive impairment was measured with the use of the Montreal Cognitive Assessment (MoCA). The nutrition parameters included: hemoglobin, red blood cells, total cholesterol and its fractions, triglycerides, total protein, albumin, urea, creatinine, phosphates, calcium and sodium. The analysis showed that albumin concentration significantly correlated with the total MoCA score and especially with the short-term memory test score. Conversely, total cholesterol, and especially LDL concentrations, were highly and negatively associated with the MoCA score. In conclusion: markers of nutritional status are correlated with the severity of CF. Individuals with malnutrition or risk of malnutrition should be screened for CF. Further studies need to be performed in this area.
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spelling pubmed-90330192022-04-23 Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report Klimkiewicz, Jakub Pankowski, Daniel Wytrychiewicz-Pankowska, Kinga Klimkiewicz, Anna Siwik, Paulina Klimczuk, Joanna Lubas, Arkadiusz Nutrients Article Numerous data indicate the presence of cognitive impairment in people who have undergone COVID-19, often called COVID Fog (CF). This phenomenon persists even 6 months after infection, and its etiology and pathogenesis are not fully known. The aim of this article was to analyze the relationship among cognitive functioning, clinical data and nutrition indexes in patients discharged from the COVID-19 hospital of the Military Institute of Medicine, Warsaw, Poland. The sample comprised 17 individuals—10 women and 7 men, with ages of 65 ± 14 years. Cognitive impairment was measured with the use of the Montreal Cognitive Assessment (MoCA). The nutrition parameters included: hemoglobin, red blood cells, total cholesterol and its fractions, triglycerides, total protein, albumin, urea, creatinine, phosphates, calcium and sodium. The analysis showed that albumin concentration significantly correlated with the total MoCA score and especially with the short-term memory test score. Conversely, total cholesterol, and especially LDL concentrations, were highly and negatively associated with the MoCA score. In conclusion: markers of nutritional status are correlated with the severity of CF. Individuals with malnutrition or risk of malnutrition should be screened for CF. Further studies need to be performed in this area. MDPI 2022-04-11 /pmc/articles/PMC9033019/ /pubmed/35458142 http://dx.doi.org/10.3390/nu14081580 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Klimkiewicz, Jakub
Pankowski, Daniel
Wytrychiewicz-Pankowska, Kinga
Klimkiewicz, Anna
Siwik, Paulina
Klimczuk, Joanna
Lubas, Arkadiusz
Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report
title Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report
title_full Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report
title_fullStr Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report
title_full_unstemmed Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report
title_short Analysis of the Relationship among Cognitive Impairment, Nutritional Indexes and the Clinical Course among COVID-19 Patients Discharged from Hospital—Preliminary Report
title_sort analysis of the relationship among cognitive impairment, nutritional indexes and the clinical course among covid-19 patients discharged from hospital—preliminary report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033019/
https://www.ncbi.nlm.nih.gov/pubmed/35458142
http://dx.doi.org/10.3390/nu14081580
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