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Integrated Quantitative Neuro-Transcriptome Analysis of Several Brain Areas in Human Trisomy 21

Background: Although Down syndrome (DS) is the most frequent human chromosomal disorder and it causes mainly intellectual disability, its clinical presentation is complex and variable. Objective: We aimed to analyze and compare the transcriptome disruption in several brain areas from individuals wit...

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Detalles Bibliográficos
Autores principales: Rodríguez-Ortiz, Alejandra, Montoya-Villegas, Julio César, García-Vallejo, Felipe, Mina-Paz, Yecid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033037/
https://www.ncbi.nlm.nih.gov/pubmed/35456434
http://dx.doi.org/10.3390/genes13040628