PCSK9 Plasma Levels Are Associated with Mechanical Vascular Impairment in Familial Hypercholesterolemia Subjects without a History of Atherosclerotic Cardiovascular Disease: Results of Six-Month Add-On PCSK9 Inhibitor Therapy

Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a key regulator of low-density lipoprotein (LDL) metabolism involved in the degradation of the low-density lipoprotein receptor (LDLR) through complex mechanisms. The PCSK9 plasma levels change according to lipid lowering therapy (LLT). Few da...

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Detalles Bibliográficos
Autores principales: Toscano, Arianna, Cinquegrani, Maria, Scuruchi, Michele, Di Pino, Antonino, Piro, Salvatore, Ferrara, Viviana, Morace, Carmela, Lo Gullo, Alberto, Imbalzano, Egidio, Purrello, Francesco, Squadrito, Giovanni, Scicali, Roberto, Mandraffino, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033040/
https://www.ncbi.nlm.nih.gov/pubmed/35454151
http://dx.doi.org/10.3390/biom12040562

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