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The Evolution of Intein-Based Affinity Methods as Reflected in 30 years of Patent History
Self-cleaving affinity tags, based on engineered intein protein domains, have been touted as a universal single step purification platform for tagless non-mAb proteins. These approaches provide all of the power and flexibility of tag-based affinity methods, but deliver a tagless target protein suita...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033041/ https://www.ncbi.nlm.nih.gov/pubmed/35463948 http://dx.doi.org/10.3389/fmolb.2022.857566 |