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EASIX and Severe Endothelial Complications After CD19-Directed CAR-T Cell Therapy—A Cohort Study

BACKGROUND: Endothelial dysfunction is associated with two main complications of chimeric antigen receptor T (CAR-T) cell therapy, cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). This study evaluates the Endothelial Activation and Stress Index (EAS...

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Detalles Bibliográficos
Autores principales: Korell, Felix, Penack, Olaf, Mattie, Mike, Schreck, Nicholas, Benner, Axel, Krzykalla, Julia, Wang, Zixing, Schmitt, Michael, Bullinger, Lars, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033201/
https://www.ncbi.nlm.nih.gov/pubmed/35464403
http://dx.doi.org/10.3389/fimmu.2022.877477