Cargando…

EASIX and Severe Endothelial Complications After CD19-Directed CAR-T Cell Therapy—A Cohort Study

BACKGROUND: Endothelial dysfunction is associated with two main complications of chimeric antigen receptor T (CAR-T) cell therapy, cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). This study evaluates the Endothelial Activation and Stress Index (EAS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Korell, Felix, Penack, Olaf, Mattie, Mike, Schreck, Nicholas, Benner, Axel, Krzykalla, Julia, Wang, Zixing, Schmitt, Michael, Bullinger, Lars, Müller-Tidow, Carsten, Dreger, Peter, Luft, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033201/ https://www.ncbi.nlm.nih.gov/pubmed/35464403 http://dx.doi.org/10.3389/fimmu.2022.877477

Ejemplares similares

Pre-transplant EASIX and sepsis after allogeneic stem cell transplantation
por: Korell, Felix, et al.
Publicado: (2022)

Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel
por: Jiang, Sihe, et al.
Publicado: (2020)

EASIX for Prediction of Outcome in Hospitalized SARS-CoV-2 Infected Patients
por: Luft, Thomas, et al.
Publicado: (2021)

Validation of pre-conditioning EASIX for prediction of sepsis after allogeneic stem cell transplantation
por: Korell, Felix, et al.
Publicado: (2023)

EASIX for prediction of survival in lower-risk myelodysplastic syndromes
por: Merz, Almuth, et al.
Publicado: (2019)

Early bilirubinemia after allogeneic stem cell transplantation—an endothelial complication
por: Dai, Hao, et al.
Publicado: (2021)

EASIX-1year and late mortality after allogeneic stem cell transplantation
por: Kordelas, Lambros, et al.
Publicado: (2023)

First third-generation CAR T cell application targeting CD19 for the treatment of systemic IgM AL amyloidosis with underlying marginal zone lymphoma
por: Korell, Felix, et al.
Publicado: (2023)

Pre-transplant testosterone and outcome of men after allogeneic stem cell transplantation
por: Radujkovic, Aleksandar, et al.
Publicado: (2020)

Infection Complications after Lymphodepletion and Dosing of Chimeric Antigen Receptor T (CAR-T) Cell Therapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia or B Cell Non-Hodgkin Lymphoma
por: Korell, Felix, et al.
Publicado: (2021)

Current Challenges in Providing Good Leukapheresis Products for Manufacturing of CAR-T Cells for Patients with Relapsed/Refractory NHL or ALL
por: Korell, Felix, et al.
Publicado: (2020)

EASIX, Modified EASIX and Simplified EASIX as an Early Predictor for Intensive Care Unit Admission and Mortality in Severe COVID-19 Patients
por: Zińczuk, Aleksander, et al.
Publicado: (2022)

Population-Based External Validation of the EASIX Scores to Predict CAR T-Cell-Related Toxicities
por: de Boer, Janneke W., et al.
Publicado: (2023)

Editorial: Endothelial Dysfunction During Inflammation and Alloimmunity
por: Penack, Olaf, et al.
Publicado: (2018)

Polymorphisms in CXCR3 ligands predict early CXCL9 recovery and severe chronic GVHD
por: Dai, Hao, et al.
Publicado: (2021)

Chimeric Antigen Receptor (CAR) T Cell Therapy in Acute Myeloid Leukemia (AML)
por: Hofmann, Susanne, et al.
Publicado: (2019)

Pre-transplant weight loss predicts inferior outcome after allogeneic stem cell transplantation in patients with myelodysplastic syndrome
por: Radujkovic, Aleksandar, et al.
Publicado: (2015)

IL-10 plus the EASIX score predict bleeding events after anti-CD19 CAR T-cell therapy
por: Wang, Xindi, et al.
Publicado: (2023)

Endothelial activation and stress index (EASIX) is a reliable predictor for overall survival in patients with multiple myeloma
por: Song, Ga-Young, et al.
Publicado: (2020)

Complications after CD19+ CAR T-Cell Therapy
por: Penack, Olaf, et al.
Publicado: (2020)

Assessment of CAR T Cell Frequencies in Axicabtagene Ciloleucel and Tisagenlecleucel Patients Using Duplex Quantitative PCR
por: Schubert, Maria-Luisa, et al.
Publicado: (2020)

P1404: IL-10 PLUS THE EASIX SCORE PREDICT BLEEDING EVENTS AFTER ANTI-CD19 CAR T-CELL THERAPY
por: Wang, Xindi, et al.
Publicado: (2023)

Optimized Assessment of qPCR-Based Vector Copy Numbers as a Safety Parameter for GMP-Grade CAR T Cells and Monitoring of Frequency in Patients
por: Kunz, Alexander, et al.
Publicado: (2020)

Interleukin-18 and Hematopoietic Recovery after Allogeneic Stem Cell Transplantation
por: Radujkovic, Aleksandar, et al.
Publicado: (2020)

The Endothelial Activation and Stress Index (EASIX) score is an independent prognostic factor in patients with diffuse large B-cell lymphoma
por: Park, Sungwoo, et al.
Publicado: (2022)

Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy
por: Yang, Mingya, et al.
Publicado: (2021)

Pre-Transplant Serum Leptin Levels and Relapse of Acute Myeloid Leukemia after Allogeneic Transplantation
por: Schwarzbich, Mark-Alexander, et al.
Publicado: (2022)

Topographic, tomographic, and corneal wavefront asymmetry in keratoconus: towards an eye asymmetry index EASIX
por: Mehlan, Juliane, et al.
Publicado: (2022)

Letermovir prophylaxis is effective in preventing cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation: single-center real-world data
por: Derigs, Patrick, et al.
Publicado: (2020)

Asymmetric dimethylarginine serum levels are associated with early mortality after allogeneic stem cell transplantation
por: Radujkovic, Aleksandar, et al.
Publicado: (2019)

Interleukin-18 and outcome after allogeneic stem cell transplantation: A retrospective cohort study
por: Radujkovic, Aleksandar, et al.
Publicado: (2019)

The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL
por: Rejeski, Kai, et al.
Publicado: (2022)

Real-world results of CAR T-cell therapy for large B-cell lymphoma with CNS involvement: a GLA/DRST study
por: Ayuk, Francis, et al.
Publicado: (2023)

Pre-sensitization of Malignant B Cells Through Venetoclax Significantly Improves the Cytotoxic Efficacy of CD19.CAR-T Cells
por: Yang, Mingya, et al.
Publicado: (2020)

Endothelial cell dysfunction: a key determinant for the outcome of allogeneic stem cell transplantation
por: Luft, Thomas, et al.
Publicado: (2021)

Comparison of single copy gene-based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19-directed CAR T cells in treated patients
por: Schubert, Maria-Luisa, et al.
Publicado: (2022)

Severe hematotoxicity after CD19 CAR-T therapy is associated with suppressive immune dysregulation and limited CAR-T expansion
por: Rejeski, Kai, et al.
Publicado: (2023)

Dynamic EASIX scores closely predict nonrelapse mortality after allogeneic hematopoietic cell transplantation
por: Nawas, Mariam T., et al.
Publicado: (2022)

EASIX Is an Accurate and Easily Available Prognostic Score in Critically Ill Patients with Advanced Liver Disease
por: Schult, David, et al.
Publicado: (2023)

P417: GENOMIC LANDSCAPE AND PROGNOSIS IN OLDER ACUTE MYELOID LEUKEMIA PATIENTS NOT ELIGIBLE FOR INTENSIVE CHEMOTHERAPY
por: Jahn, Ekaterina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bspra0jq78ja0e9u98si1s898i