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Pd-catalyzed synthesis of 1-(hetero)aryl-2,2,2-trichloroethanols using chloral hydrate and (hetero)arylboroxines

1-(Hetero)aryl-2,2,2-trichloroethanols are useful key intermediates for the synthesis of various bioactive compounds. Herein, we describe N-heterocyclic carbene (NHC)-coordinated cyclometallated palladium complex (CYP)-catalyzed (hetero)aryl addition of chloral hydrate using (hetero)arylboroxines, p...

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Detalles Bibliográficos
Autores principales:	Shimizu, Minori, Okuda, Yuta, Toyoda, Koki, Akiyama, Ryo, Shinozaki, Hiraku, Yamamoto, Tetsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033206/ https://www.ncbi.nlm.nih.gov/pubmed/35480199 http://dx.doi.org/10.1039/d1ra02403e

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