Development of a caffeic acid–phthalimide hybrid compound for NADPH oxidase inhibition

NADPH oxidases are pharmacological targets for the treatment of inflammation-based diseases. This work presents the synthesis and study of a caffeic acid/phthalimide hybrid compound (C2) as a potential inhibitor of NADPH oxidases. Throughout the study, we have compared compound C2 with its precursor...

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Detalles Bibliográficos
Autores principales: dos Santos, Willian Henrique, Yoguim, Maurício Ikeda, Daré, Regina Gomes, da Silva-Filho, Luiz Carlos, Lautenschlager, Sueli Oliveira Silva, Ximenes, Valdecir Farias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033209/
https://www.ncbi.nlm.nih.gov/pubmed/35480205
http://dx.doi.org/10.1039/d1ra01066b

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