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Silylative aromatization of p-quinone methides under metal and solvent free conditions

A base-mediated silylation reaction leading to benzyl silanes has been developed. Under transition-metal and solvent free conditions, the silylation of a wide array of p-quinone methides is achieved using a Cs(2)CO(3) catalyst in yields up to 96%. Carboxylation of the as-obtained organosilane with g...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Wu, Yuzhu, Duan, Wenzeng, Ma, Yudao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033227/
https://www.ncbi.nlm.nih.gov/pubmed/35480172
http://dx.doi.org/10.1039/d1ra03193g
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author Li, Tingting
Wu, Yuzhu
Duan, Wenzeng
Ma, Yudao
author_facet Li, Tingting
Wu, Yuzhu
Duan, Wenzeng
Ma, Yudao
author_sort Li, Tingting
collection PubMed
description A base-mediated silylation reaction leading to benzyl silanes has been developed. Under transition-metal and solvent free conditions, the silylation of a wide array of p-quinone methides is achieved using a Cs(2)CO(3) catalyst in yields up to 96%. Carboxylation of the as-obtained organosilane with gaseous CO(2) provides a new synthetic protocol for the preparation of carboxylic acid.
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spelling pubmed-90332272022-04-26 Silylative aromatization of p-quinone methides under metal and solvent free conditions Li, Tingting Wu, Yuzhu Duan, Wenzeng Ma, Yudao RSC Adv Chemistry A base-mediated silylation reaction leading to benzyl silanes has been developed. Under transition-metal and solvent free conditions, the silylation of a wide array of p-quinone methides is achieved using a Cs(2)CO(3) catalyst in yields up to 96%. Carboxylation of the as-obtained organosilane with gaseous CO(2) provides a new synthetic protocol for the preparation of carboxylic acid. The Royal Society of Chemistry 2021-05-18 /pmc/articles/PMC9033227/ /pubmed/35480172 http://dx.doi.org/10.1039/d1ra03193g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Li, Tingting
Wu, Yuzhu
Duan, Wenzeng
Ma, Yudao
Silylative aromatization of p-quinone methides under metal and solvent free conditions
title Silylative aromatization of p-quinone methides under metal and solvent free conditions
title_full Silylative aromatization of p-quinone methides under metal and solvent free conditions
title_fullStr Silylative aromatization of p-quinone methides under metal and solvent free conditions
title_full_unstemmed Silylative aromatization of p-quinone methides under metal and solvent free conditions
title_short Silylative aromatization of p-quinone methides under metal and solvent free conditions
title_sort silylative aromatization of p-quinone methides under metal and solvent free conditions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033227/
https://www.ncbi.nlm.nih.gov/pubmed/35480172
http://dx.doi.org/10.1039/d1ra03193g
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AT duanwenzeng silylativearomatizationofpquinonemethidesundermetalandsolventfreeconditions
AT mayudao silylativearomatizationofpquinonemethidesundermetalandsolventfreeconditions