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Copper-catalyzed aerobic oxidative radical alkoxycyclization of tryptamines to access 3-alkoxypyrroloindolines

We report a copper-catalyzed alkoxycyclization of tryptamine derivatives with O(2) as the sole oxidant, leading to a variety of C3a-alkoxypyrroloindolines in good yields with high diastereoselectivities. This reaction involves an interesting double catalytic cycle in which copper-catalyzed carboamin...

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Detalles Bibliográficos
Autores principales:	Wang, Wei, Song, Jun-Rong, Li, Zhi-Yao, Zhong, Ting, Chi, Qin, Ren, Hai, Pan, Wei-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033248/ https://www.ncbi.nlm.nih.gov/pubmed/35480191 http://dx.doi.org/10.1039/d1ra02679h

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