Pocket delipidation induced by membrane tension or modification leads to a structurally analogous mechanosensitive channel state

The mechanosensitive ion channel of large conductance MscL gates in response to membrane tension changes. Lipid removal from transmembrane pockets leads to a concerted structural and functional MscL response, but it remains unknown whether there is a correlation between the tension-mediated state an...

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Detalles Bibliográficos
Autores principales: Wang, Bolin, Lane, Benjamin J., Kapsalis, Charalampos, Ault, James R., Sobott, Frank, El Mkami, Hassane, Calabrese, Antonio N., Kalli, Antreas C., Pliotas, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033278/
https://www.ncbi.nlm.nih.gov/pubmed/34986323
http://dx.doi.org/10.1016/j.str.2021.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033278/
https://www.ncbi.nlm.nih.gov/pubmed/34986323
http://dx.doi.org/10.1016/j.str.2021.12.004

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