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An extended epidemic model with vaccination: Weak-immune SIRVI

A new modification of the SIR epidemic model incorporating vaccination is proposed in the present paper. The recent trend of vaccinating against COVID-19 pandemic reveals a strong control of infectious disease. On the other hand, it is observed in some countries that, the vaccine application offers...

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Autor principal: Turkyilmazoglu, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033298/
https://www.ncbi.nlm.nih.gov/pubmed/35498560
http://dx.doi.org/10.1016/j.physa.2022.127429
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author Turkyilmazoglu, Mustafa
author_facet Turkyilmazoglu, Mustafa
author_sort Turkyilmazoglu, Mustafa
collection PubMed
description A new modification of the SIR epidemic model incorporating vaccination is proposed in the present paper. The recent trend of vaccinating against COVID-19 pandemic reveals a strong control of infectious disease. On the other hand, it is observed in some countries that, the vaccine application offers less control over the spread of virus, since some portion of vaccinated people is not totally protected/immuned and viable to infection again after a while due to weak/loss immunity offered by the vaccine. This requires transition from vaccinated department to infected for COVID-19. This character of COVID-19 helps us reconsideration of the vaccinated department by letting some part of it being exposed to the infection again. Taking this into account, as a result of modification of the SIR model, the epidemiology is now governed with three main epidemic dimensionless parameters, having provided an initial fraction of infected individuals. The dimensionless model with these parameters is analyzed initially from the stability point of view. The effects of weak immunity are then illustrated numerically on some chosen parameter range. How some of the countries applying the COVID-19 vaccine programs affected by weak/loss immunity is eventually examined with the modified model. The rate of vaccination as well as the basic Reproduction number are found to affect the epidemic demography of the population subject to weak or loss of immunity. In the case of a high vaccination rate, the countries are not anticipated to be highly influenced by the weak immunity of low level, whereas weak immunity prolongs the contagious disease by appearance of secondary multiple peaks in the epidemic compartments with relatively small vaccination rates and basic Reproductive numbers.
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spelling pubmed-90332982022-04-25 An extended epidemic model with vaccination: Weak-immune SIRVI Turkyilmazoglu, Mustafa Physica A Article A new modification of the SIR epidemic model incorporating vaccination is proposed in the present paper. The recent trend of vaccinating against COVID-19 pandemic reveals a strong control of infectious disease. On the other hand, it is observed in some countries that, the vaccine application offers less control over the spread of virus, since some portion of vaccinated people is not totally protected/immuned and viable to infection again after a while due to weak/loss immunity offered by the vaccine. This requires transition from vaccinated department to infected for COVID-19. This character of COVID-19 helps us reconsideration of the vaccinated department by letting some part of it being exposed to the infection again. Taking this into account, as a result of modification of the SIR model, the epidemiology is now governed with three main epidemic dimensionless parameters, having provided an initial fraction of infected individuals. The dimensionless model with these parameters is analyzed initially from the stability point of view. The effects of weak immunity are then illustrated numerically on some chosen parameter range. How some of the countries applying the COVID-19 vaccine programs affected by weak/loss immunity is eventually examined with the modified model. The rate of vaccination as well as the basic Reproduction number are found to affect the epidemic demography of the population subject to weak or loss of immunity. In the case of a high vaccination rate, the countries are not anticipated to be highly influenced by the weak immunity of low level, whereas weak immunity prolongs the contagious disease by appearance of secondary multiple peaks in the epidemic compartments with relatively small vaccination rates and basic Reproductive numbers. Elsevier B.V. 2022-07-15 2022-04-22 /pmc/articles/PMC9033298/ /pubmed/35498560 http://dx.doi.org/10.1016/j.physa.2022.127429 Text en © 2022 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Turkyilmazoglu, Mustafa
An extended epidemic model with vaccination: Weak-immune SIRVI
title An extended epidemic model with vaccination: Weak-immune SIRVI
title_full An extended epidemic model with vaccination: Weak-immune SIRVI
title_fullStr An extended epidemic model with vaccination: Weak-immune SIRVI
title_full_unstemmed An extended epidemic model with vaccination: Weak-immune SIRVI
title_short An extended epidemic model with vaccination: Weak-immune SIRVI
title_sort extended epidemic model with vaccination: weak-immune sirvi
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033298/
https://www.ncbi.nlm.nih.gov/pubmed/35498560
http://dx.doi.org/10.1016/j.physa.2022.127429
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