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Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model

Phage, the most prevalent creature on the planet, serves a variety of critical roles. Phage's primary role is to facilitate gene-to-gene communication. The phage proteins can be defined as the virion proteins and the nonvirion ones. Nowadays, experimental identification is a difficult process t...

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Autores principales: Bao, Wenzheng, Cui, Qingyu, Chen, Baitong, Yang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033350/
https://www.ncbi.nlm.nih.gov/pubmed/35465015
http://dx.doi.org/10.1155/2022/9470683
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author Bao, Wenzheng
Cui, Qingyu
Chen, Baitong
Yang, Bin
author_facet Bao, Wenzheng
Cui, Qingyu
Chen, Baitong
Yang, Bin
author_sort Bao, Wenzheng
collection PubMed
description Phage, the most prevalent creature on the planet, serves a variety of critical roles. Phage's primary role is to facilitate gene-to-gene communication. The phage proteins can be defined as the virion proteins and the nonvirion ones. Nowadays, experimental identification is a difficult process that necessitates a significant amount of laboratory time and expense. Considering such situation, it is critical to design practical calculating techniques and develop well-performance tools. In this work, the Phage_UniR_LGBM has been proposed to classify the virion proteins. In detailed, such model utilizes the UniRep as the feature and the LightGBM algorithm as the classification model. And then, the training data train the model, and the testing data test the model with the cross-validation. The Phage_UniR_LGBM was compared with the several state-of-the-art features and classification algorithms. The performances of the Phage_UniR_LGBM are 88.51% in Sp,89.89% in Sn, 89.18% in Acc, 0.7873 in MCC, and 0.8925 in F1 score.
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spelling pubmed-90333502022-04-23 Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model Bao, Wenzheng Cui, Qingyu Chen, Baitong Yang, Bin Comput Math Methods Med Research Article Phage, the most prevalent creature on the planet, serves a variety of critical roles. Phage's primary role is to facilitate gene-to-gene communication. The phage proteins can be defined as the virion proteins and the nonvirion ones. Nowadays, experimental identification is a difficult process that necessitates a significant amount of laboratory time and expense. Considering such situation, it is critical to design practical calculating techniques and develop well-performance tools. In this work, the Phage_UniR_LGBM has been proposed to classify the virion proteins. In detailed, such model utilizes the UniRep as the feature and the LightGBM algorithm as the classification model. And then, the training data train the model, and the testing data test the model with the cross-validation. The Phage_UniR_LGBM was compared with the several state-of-the-art features and classification algorithms. The performances of the Phage_UniR_LGBM are 88.51% in Sp,89.89% in Sn, 89.18% in Acc, 0.7873 in MCC, and 0.8925 in F1 score. Hindawi 2022-04-15 /pmc/articles/PMC9033350/ /pubmed/35465015 http://dx.doi.org/10.1155/2022/9470683 Text en Copyright © 2022 Wenzheng Bao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bao, Wenzheng
Cui, Qingyu
Chen, Baitong
Yang, Bin
Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model
title Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model
title_full Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model
title_fullStr Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model
title_full_unstemmed Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model
title_short Phage_UniR_LGBM: Phage Virion Proteins Classification with UniRep Features and LightGBM Model
title_sort phage_unir_lgbm: phage virion proteins classification with unirep features and lightgbm model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033350/
https://www.ncbi.nlm.nih.gov/pubmed/35465015
http://dx.doi.org/10.1155/2022/9470683
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