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Activation of TGR5 Ameliorates Streptozotocin-Induced Cognitive Impairment by Modulating Apoptosis, Neurogenesis, and Neuronal Firing
Takeda G protein-coupled receptor 5 (TGR5) is the first known G protein-coupled receptor specific for bile acids and is recognized as a new and critical target for type 2 diabetes and metabolic syndrome. It is expressed in many brain regions associated with memory such as the hippocampus and frontal...
Autores principales: | Mu, Ronghao, Wu, Xian, Yuan, Danhua, Zhao, Jiajia, Tang, Susu, Hong, Hao, Long, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033389/ https://www.ncbi.nlm.nih.gov/pubmed/35464765 http://dx.doi.org/10.1155/2022/3716609 |
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