Cargando…

Synthesis and biological evaluation of novel artemisone–piperazine–tetronamide hybrids

For the first time, six novel artemisone–piperazine–tetronamide hybrids (12a–f) were efficiently synthesised from dihydroartemisinin (DHA) and investigated for their in vitro cytotoxicity against some human cancer cells and benign cells. All the targets showed good cytotoxic activity in vitro. Hybri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Meng-Xue, Yu, Jia-Ying, Liu, Xin-Xin, Li, Xue-Qiang, Yang, Jin-Hui, Zhang, Meng-Wei, Yang, Pei-Wen, Zhang, Si-Si, He, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033422/ https://www.ncbi.nlm.nih.gov/pubmed/35480921 http://dx.doi.org/10.1039/d1ra00750e

Ejemplares similares

Synthesis and Biological Activity of Myricetin Derivatives Containing Pyrazole Piperazine Amide
por: Liu, Fang, et al.
Publicado: (2023)

Facile synthesis and biological evaluation of tryptamine-piperazine-2,5-dione conjugates as anticancer agents
por: Meng, Jiang-Ping, et al.
Publicado: (2021)

Synthesis and Biological Evaluation of Piperazine Hybridized Coumarin Indolylcyanoenones with Antibacterial Potential
por: Zeng, Chunmei, et al.
Publicado: (2023)

Effects of Synthetic Tetronamides and Methylated Denigrins on Bacterial Quorum Sensing and Biofilm Formation
por: Roy, Sweta, et al.
Publicado: (2023)

Artemisone effective against murine cerebral malaria
por: Waknine-Grinberg, Judith H, et al.
Publicado: (2010)

Controlled release of artemisone for the treatment of experimental cerebral malaria
por: Golenser, Jacob, et al.
Publicado: (2017)

Synthesis and biological evaluation of a new class of multi-target heterocycle piperazine derivatives as potential antipsychotics
por: Gao, Lanchang, et al.
Publicado: (2021)

DABCO bond cleavage for the synthesis of piperazine derivatives
por: Halimehjani, Azim Ziyaei, et al.
Publicado: (2019)

Elimination of Schistosoma mansoni in infected mice by slow release of artemisone
por: Gold, Daniel, et al.
Publicado: (2017)

Oral Administration of Artemisone for the Treatment of Schistosomiasis: Formulation Challenges and In Vivo Efficacy
por: Zech, Johanna, et al.
Publicado: (2020)

An antibacterial and biocompatible piperazine polymer
por: Zhang, Maolan, et al.
Publicado: (2019)

Synthesis and biological evaluation of indazole derivatives as anti-cancer agents
por: Wei, Wei, et al.
Publicado: (2021)

Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue
por: Ng, Jerome P. L., et al.
Publicado: (2022)

1,4-Dibenzylpiperazine
por: Zhang, Meng, et al.
Publicado: (2010)

Synthesis and characterization of potential polycyclic energetic materials using bicyclic triazole and azetidine structures as building blocks
por: Yang, Xin-bo, et al.
Publicado: (2023)

2,2′-(Piperazine-1,4-diyl)diacetonitrile
por: Gao, Wei, et al.
Publicado: (2012)

Anti-Melanoma Activities of Artemisone and Prenylated Amino-Artemisinins in Combination With Known Anticancer Drugs
por: Wong, Ho Ning, et al.
Publicado: (2020)

Treatment of Experimental Cerebral Malaria by Slow Release of Artemisone From Injectable Pasty Formulation
por: Golenser, Jacob, et al.
Publicado: (2020)

One-pot four-component synthesis of novel isothiourea-ethylene-tethered-piperazine derivatives
por: Hajizadeh, Fatima, et al.
Publicado: (2023)

A study on the self-assembly mode and supramolecular framework of complexes of cucurbit[6]urils and 1-(4-methoxyphenyl)piperazine
por: Jin, Yanmei, et al.
Publicado: (2020)

Recent progress toward the asymmetric synthesis of carbon-substituted piperazine pharmacophores and oxidative related heterocycles
por: Magriotis, Plato A.
Publicado: (2020)

One-pot synthesis of a [c2]daisy-chain-containing hetero[4]rotaxane via a self-sorting strategy
por: Fu, Xin, et al.
Publicado: (2016)

Research progress of catalysts for synthesis of low-carbon alcohols from synthesis gas
por: Xue, Xiaoxiao, et al.
Publicado: (2021)

Piperazine based antimicrobial polymers: a review
por: Jalageri, Manohara Dhulappa, et al.
Publicado: (2021)

Efficient Treatment of Experimental Cerebral Malaria by an Artemisone-SMEDDS System: Impact of Application Route and Dosing Frequency
por: Zech, Johanna, et al.
Publicado: (2021)

A facile synthesis of CuSe nanosheets for high-performance sodium-ion hybrid capacitors
por: Chen, Chen, et al.
Publicado: (2022)

A novel cellulose/chitosan composite nanofiltration membrane prepared with piperazine and trimesoyl chloride by interfacial polymerization
por: Weng, Rengui, et al.
Publicado: (2020)

Copper mediated one-pot synthesis of quinazolinones and exploration of piperazine linked quinazoline derivatives as anti-mycobacterial agents
por: Malasala, Satyaveni, et al.
Publicado: (2020)

Conformationally confined three-armed supramolecular folding for boosting near-infrared biological imaging
por: Wang, Hui-Juan, et al.
Publicado: (2023)

Fabrication of a hybrid ultrafiltration membrane based on MoS(2) modified with dopamine and polyethyleneimine
por: Wen, Xin, et al.
Publicado: (2021)

The piperazine compound ASP activates an auxin response in Arabidopsis thaliana
por: Xu, Fengyang, et al.
Publicado: (2020)

Comparison of the physical and thermodynamic stability of amorphous azelnidipine and its coamorphous phase with piperazine
por: Du, Shuang, et al.
Publicado: (2018)

Nickel-phytic acid hybrid for highly efficient electrocatalytic upgrading of HMF
por: Liu, Shuyi, et al.
Publicado: (2023)

Design, Synthesis, and Anti-PVY Biological Activity of 1,3,5-Triazine Derivatives Containing Piperazine Structure
por: Bai, Lian, et al.
Publicado: (2023)

Synthesis, structure–fluorescence relationships and density functional theory studies of novel naphthalimide–piperazine–pyridine-based polystyrene sensors for Hg(ii) detection
por: Liu, Yuanyuan, et al.
Publicado: (2020)

Tumor Microenvironmental Responsive Liposomes Simultaneously Encapsulating Biological and Chemotherapeutic Drugs for Enhancing Antitumor Efficacy of NSCLC
por: Kong, Liang, et al.
Publicado: (2020)

Synthesis of Nickel In Situ Modified SAPO-11 Molecular Sieves and Hydroisomerization Performance of Their NiWS Supported Catalysts
por: Dai, Xiaojun, et al.
Publicado: (2021)

A mild one-pot synthesis of 2-iminothiazolines from thioureas and 1-bromo-1-nitroalkenes
por: Xu, Yuan, et al.
Publicado: (2021)

Design, Synthesis, and Biological Evaluation of N-Acyl-Homoserine Lactone Analogs of Quorum Sensing in Pseudomonas aeruginosa
por: Wei, Zhenyu, et al.
Publicado: (2022)

Synthesis and Biological Evaluation of 3-(Pyridine-3-yl)-2-Oxazolidinone Derivatives as Antibacterial Agents
por: Jin, Bo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h4rbf1jl5m11dggq9e8i252n02