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Is Omicron the end of pandemic or start of a new innings?

In the middle of November 2021, Omicron (B.1.1.529), a novel variant of SARS-CoV-2 was identified in South Africa. Owing to continuous increasing cases with rapid transmissibility and immune evasion, the World Health Organization (WHO) has categorized this strain as a variant of concern (VOC). In to...

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Autores principales: Das, Swarnali, Samanta, Sovan, Banerjee, Jhimli, Pal, Amitava, Giri, Biplab, Kar, Suvrendu Sankar, Dash, Sandeep Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033632/
https://www.ncbi.nlm.nih.gov/pubmed/35472451
http://dx.doi.org/10.1016/j.tmaid.2022.102332
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author Das, Swarnali
Samanta, Sovan
Banerjee, Jhimli
Pal, Amitava
Giri, Biplab
Kar, Suvrendu Sankar
Dash, Sandeep Kumar
author_facet Das, Swarnali
Samanta, Sovan
Banerjee, Jhimli
Pal, Amitava
Giri, Biplab
Kar, Suvrendu Sankar
Dash, Sandeep Kumar
author_sort Das, Swarnali
collection PubMed
description In the middle of November 2021, Omicron (B.1.1.529), a novel variant of SARS-CoV-2 was identified in South Africa. Owing to continuous increasing cases with rapid transmissibility and immune evasion, the World Health Organization (WHO) has categorized this strain as a variant of concern (VOC). In total, over 60 mutations have been identified in Omicron (BA.1) and latterly, its three sub-lineages (BA.1.1, BA.2, and BA.3) have also been found with additional mutations and pathogenicity. The highly contagious Omicron causes less severe sickness than Delta, but it is still dangerous for those who have not been vaccinated. Following the unique identification of the Omicron variant, a fresh debate has erupted regarding the natural vaccines. A number of experts believe that Omicron can work as a natural vaccine, because it is similar to live attenuated vaccines in certain ways. Additionally, it was highlighted that the high rate of antibody generation in individuals cured of Omicron provide suggestive evidence in favor of those researchers who claimed Omicron acts as natural vaccine. Some disagreements also noted, as it also has tremendous health effects and high infection rate, as similar to the prior variants. This review summarizes the contradictory scenario among the scientists about Omicron variant.
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spelling pubmed-90336322022-04-25 Is Omicron the end of pandemic or start of a new innings? Das, Swarnali Samanta, Sovan Banerjee, Jhimli Pal, Amitava Giri, Biplab Kar, Suvrendu Sankar Dash, Sandeep Kumar Travel Med Infect Dis Article In the middle of November 2021, Omicron (B.1.1.529), a novel variant of SARS-CoV-2 was identified in South Africa. Owing to continuous increasing cases with rapid transmissibility and immune evasion, the World Health Organization (WHO) has categorized this strain as a variant of concern (VOC). In total, over 60 mutations have been identified in Omicron (BA.1) and latterly, its three sub-lineages (BA.1.1, BA.2, and BA.3) have also been found with additional mutations and pathogenicity. The highly contagious Omicron causes less severe sickness than Delta, but it is still dangerous for those who have not been vaccinated. Following the unique identification of the Omicron variant, a fresh debate has erupted regarding the natural vaccines. A number of experts believe that Omicron can work as a natural vaccine, because it is similar to live attenuated vaccines in certain ways. Additionally, it was highlighted that the high rate of antibody generation in individuals cured of Omicron provide suggestive evidence in favor of those researchers who claimed Omicron acts as natural vaccine. Some disagreements also noted, as it also has tremendous health effects and high infection rate, as similar to the prior variants. This review summarizes the contradictory scenario among the scientists about Omicron variant. Elsevier Ltd. 2022 2022-04-23 /pmc/articles/PMC9033632/ /pubmed/35472451 http://dx.doi.org/10.1016/j.tmaid.2022.102332 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Das, Swarnali
Samanta, Sovan
Banerjee, Jhimli
Pal, Amitava
Giri, Biplab
Kar, Suvrendu Sankar
Dash, Sandeep Kumar
Is Omicron the end of pandemic or start of a new innings?
title Is Omicron the end of pandemic or start of a new innings?
title_full Is Omicron the end of pandemic or start of a new innings?
title_fullStr Is Omicron the end of pandemic or start of a new innings?
title_full_unstemmed Is Omicron the end of pandemic or start of a new innings?
title_short Is Omicron the end of pandemic or start of a new innings?
title_sort is omicron the end of pandemic or start of a new innings?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033632/
https://www.ncbi.nlm.nih.gov/pubmed/35472451
http://dx.doi.org/10.1016/j.tmaid.2022.102332
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