CinA mediates multidrug tolerance in Mycobacterium tuberculosis

The ability of Mycobacterium tuberculosis (Mtb) to resist and tolerate antibiotics complicates the development of improved tuberculosis (TB) chemotherapies. Here we define the Mtb protein CinA as a major determinant of drug tolerance and as a potential target to shorten TB chemotherapy. By reducing...

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Detalles Bibliográficos
Autores principales: Kreutzfeldt, Kaj M., Jansen, Robert S., Hartman, Travis E., Gouzy, Alexandre, Wang, Ruojun, Krieger, Inna V., Zimmerman, Matthew D., Gengenbacher, Martin, Sarathy, Jansy P., Xie, Min, Dartois, Véronique, Sacchettini, James C., Rhee, Kyu Y., Schnappinger, Dirk, Ehrt, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033802/
https://www.ncbi.nlm.nih.gov/pubmed/35459278
http://dx.doi.org/10.1038/s41467-022-29832-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033802/
https://www.ncbi.nlm.nih.gov/pubmed/35459278
http://dx.doi.org/10.1038/s41467-022-29832-1

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