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5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction

Blockade of N-methyl-D-aspartate receptors (NMDAR) is known to augment cortical serotonin 2A receptors (5-HT2ARs), which is implicated in psychosis. However, the pathways from NMDAR hypofunction to 5-HT2AR up-regulation are unclear. Here we addressed in mice whether genetic deletion of the indispens...

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Detalles Bibliográficos
Autores principales:	Nakao, Kazuhito, Singh, Mahendra, Sapkota, Kiran, Fitzgerald, Andrew, Hablitz, John J., Nakazawa, Kazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033804/ https://www.ncbi.nlm.nih.gov/pubmed/35459266 http://dx.doi.org/10.1038/s41398-022-01930-0

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