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Determination of key residues in MRGPRX2 to enhance pseudo-allergic reactions induced by fluoroquinolones

MAS-related G protein-coupled receptor X2 (MRGPRX2), expressed in human mast cells, is associated with drug-induced pseudo-allergic reactions. Dogs are highly sensitive to the anaphylactoid reactions induced by certain drugs including fluoroquinolones. Recently, dog MRGPRX2 was identified as a funct...

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Detalles Bibliográficos
Autores principales:	Hamamura-Yasuno, Eri, Matsushita, Junya, Sato, Seiji, Shimada, Takashi, Tsuchiya, Yoshimi, Fujimoto, Kazunori, Mori, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9033836/ https://www.ncbi.nlm.nih.gov/pubmed/35459883 http://dx.doi.org/10.1038/s41598-022-10549-6

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