Iridium-catalyzed regioselective C–H sulfonamidation of 1,2,4-thiadiazoles with sulfonyl azides in water

We have developed a regioselective C–N cross-coupling of 1,2,4-thiadiazoles with sulfonyl azides through iridium catalysis in water. This method tactically linked the 1,2,4-thiadiazoles and sulfonamides together, and the novel molecules increased the diversity of 1,2,4-thiadiazoles which may have po...

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Detalles Bibliográficos
Autores principales: Cao, Xian-Ting, Wei, Su-Ning, Sun, Hao-Tian, Li, Meng, Zheng, Zuo-Ling, Wang, Guannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034132/
https://www.ncbi.nlm.nih.gov/pubmed/35480792
http://dx.doi.org/10.1039/d1ra04450h
Descripción
Sumario:We have developed a regioselective C–N cross-coupling of 1,2,4-thiadiazoles with sulfonyl azides through iridium catalysis in water. This method tactically linked the 1,2,4-thiadiazoles and sulfonamides together, and the novel molecules increased the diversity of 1,2,4-thiadiazoles which may have potential applications.

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