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Compartmentalized cross-linked enzyme nano aggregates (c-CLEnAs) toward pharmaceutical transformations

A new immobilization strategy using compartmentalized nanoreactors is herein reported for two biocatalytic processes: (1) N-acetylneuraminate lyase (NAL) is internalized in NAL-c-CLEnAs and used in a continuous flow aldol condensation of N-acetyl-d-mannosamine with sodium pyruvate to N-acetylneurami...

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Detalles Bibliográficos
Autores principales: de Martino, M. Teresa, Tonin, Fabio, Bloemendal, Victor R. L. J., Hanefeld, Ulf, Rutjes, Floris P. J. T., van Hest, Jan C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034143/
https://www.ncbi.nlm.nih.gov/pubmed/35478789
http://dx.doi.org/10.1039/d1ra04332c