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Human infection studies: Key considerations for challenge agent development and production
Human infection (or challenge) studies involve the intentional administration of a pathogen (challenge agent) to volunteers. The selection, isolation, development and production of the challenge agent is one of the first steps in developing a challenge study and critical for minimising the risk to v...
Autores principales: | Balasingam, Shobana, Meillon, Sarah, Chui, Cecilia, Mann, Alex, La, Carine, Weller, Charlotte L., King, Deborah F., Smith, Emma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034172/ https://www.ncbi.nlm.nih.gov/pubmed/35505774 http://dx.doi.org/10.12688/wellcomeopenres.17869.1 |
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