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Characterization and application of natural and recombinant butelase-1 to improve industrial enzymes by end-to-end circularization
Butelase-1, an asparaginyl endopeptidase or legumain, is the prototypical and fastest known Asn/Asp-specific peptide ligase. It is highly useful for engineering and macrocyclization of peptides and proteins. However, certain biochemical properties and applications of naturally occurring and recombin...
Autores principales: | Hemu, Xinya, Zhang, Xiaohong, Nguyen, Giang K. T., To, Janet, Serra, Aida, Loo, Shining, Sze, Siu Kwan, Liu, Chuan-Fa, Tam, James P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034278/ https://www.ncbi.nlm.nih.gov/pubmed/35480425 http://dx.doi.org/10.1039/d1ra03763c |
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